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先天性牙齿异常与错牙合畸形:存在基因关联?

Congenital tooth anomalies and malocclusions: a genetic link?

作者信息

Basdra E K, Kiokpasoglou M N, Komposch G

机构信息

Department of Orthodontics, University of Heidelberg, Germany.

出版信息

Eur J Orthod. 2001 Apr;23(2):145-51. doi: 10.1093/ejo/23.2.145.

DOI:10.1093/ejo/23.2.145
PMID:11398552
Abstract

The aim of the present study was to investigate putative relationships between different malocclusions such as Class III and Class II division 1, and congenital tooth anomalies. Two-hundred Class III and 215 Class II division 1 patients were examined for the presence of any of the following congenital tooth anomalies: maxillary incisor hypodontia, maxillary canine impaction, transpositions, supernumerary teeth, and tooth agenesis. Their occurrence rates were then calculated as a percentage of the total sample and were compared for statistical differences. The results revealed no statistical difference (P > 0.05) in the occurrence rates of upper lateral incisor agenesis, peg-shaped laterals, impacted canines, or supernumerary teeth between the Class III and the Class II division 1 malocclusions. When the occurrence rate of all congenital tooth anomalies was compared between the two malocclusions, Class III subjects showed significantly higher rates (P < 0.05). Comparison with published surveys on general populations showed similar occurrence rates. It can be concluded that subjects with Class III and Class II division 1 malocclusions show patterns of congenital tooth anomalies similar to those observed in the general population. Congenital tooth anomalies may represent another criterion for the study of malocclusion, with respect to their origin and development.

摘要

本研究的目的是调查不同错牙合畸形(如Ⅲ类错牙合和Ⅱ类1分类错牙合)与先天性牙齿异常之间的假定关系。对200例Ⅲ类错牙合患者和215例Ⅱ类1分类错牙合患者进行检查,以确定是否存在以下任何一种先天性牙齿异常:上颌切牙缺失、上颌尖牙阻生、牙位异常、多生牙和牙齿发育不全。然后计算它们的发生率,以占总样本的百分比表示,并比较其统计学差异。结果显示,Ⅲ类错牙合和Ⅱ类1分类错牙合在上颌侧切牙发育不全、钉状侧切牙、阻生尖牙或多生牙的发生率上无统计学差异(P>0.05)。当比较这两种错牙合畸形中所有先天性牙齿异常的发生率时,Ⅲ类错牙合患者的发生率显著更高(P<0.05)。与已发表的关于普通人群的调查结果比较,发生率相似。可以得出结论,Ⅲ类错牙合和Ⅱ类1分类错牙合患者的先天性牙齿异常模式与普通人群中观察到的相似。就先天性牙齿异常的起源和发育而言,其可能代表错牙合研究的另一个标准。

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