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心肌病的磁共振成像

MRI of the cardiomyopathies.

作者信息

Di Cesare E

机构信息

Department of Radiology, University of L'Aquila, S. Salvatore Hospital of Coppito, 67100, L'Aquila, Italy.

出版信息

Eur J Radiol. 2001 Jun;38(3):179-84. doi: 10.1016/s0720-048x(01)00311-4.

Abstract

We examined the potentialities of Magnetic resonance imaging (MRI) in the evaluation of the main cardiomyopathies: hypertrophic, dilated, restrictive and arrhythmogenic right ventricular. The hypertrophic cardiomyopathy is generally adequately investigated by echocardiography, that well defines the myocardial thickening and the obstruction of the left ventricular output. However, by echocardiography we still have difficulties in the evaluation of the apex of the left ventricle and the right ventricle involvement. MRI provides a complete evaluation of the heart with a clear evidence also of the echocardiographic dark zones by means of a clear evidence of the apex of the right ventricle. The dilated form is also well investigated by MRI that provides a clear evaluation of the volumes, mass and ejection fraction by means of the 3D analysis including conditions of the ventricular remodelling. Moreover, this technique helps in the differential diagnosis of acute myocarditis. In the acute phase of myocarditis (first 2 weeks), in fact, the myocardium produces high signal intensity on the T2 weighted sequences due to the presence of oedema. The third form of cardiomyopathy is the restrictive one, characterised by reduced diastolic filling and diastolic volume, normality of the systolic function and parietal thickness, interstitial fibrosis and enlargement of both atria. The mean potentiality of MRI is related to the differential diagnosis with constrictive pericarditis. Only in the former, the pericardium appears irregularly thickened with areas exceeding 4 mm of pericardial thickness. Finally, the right ventricular arrhythmogenic cardiomyopathy represents the main indication to MRI evaluation. With this imaging modality we are can obtain a clear morpho-functional evaluation of the right ventricle and distinguish the intramyocardial adipose substitution characterised by areas of high signal in the myocardium.

摘要

我们研究了磁共振成像(MRI)在评估主要心肌病方面的潜力:肥厚型、扩张型、限制型和致心律失常性右心室心肌病。肥厚型心肌病通常通过超声心动图进行充分检查,超声心动图能很好地界定心肌增厚和左心室流出道梗阻情况。然而,通过超声心动图评估左心室心尖和右心室受累情况仍存在困难。MRI能对心脏进行全面评估,通过清晰显示右心室心尖,也能明确超声心动图显示的暗区。扩张型心肌病同样能通过MRI进行很好的检查,MRI借助三维分析能清晰评估心室容积、心肌质量和射血分数,包括心室重构情况。此外,这项技术有助于急性心肌炎的鉴别诊断。事实上,在心肌炎急性期(最初2周),由于存在水肿,心肌在T2加权序列上表现为高信号强度。第三种心肌病是限制型心肌病,其特征为舒张期充盈和舒张容积减少、收缩功能及心肌厚度正常、间质纤维化以及双心房增大。MRI的主要潜力在于与缩窄性心包炎进行鉴别诊断。只有在前者中,心包表现为不规则增厚,心包厚度超过4mm。最后,右心室致心律失常性心肌病是MRI评估的主要指征。通过这种成像方式,我们可以对右心室进行清晰的形态功能评估,并区分以心肌内高信号区域为特征的心肌脂肪替代。

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