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播散性肺结核伴严重免疫性溶血性贫血及抗结核治疗反应

Severe immune hemolytic anemia in disseminated tuberculosis with response to antituberculosis therapy.

作者信息

Kuo P H, Yang P C, Kuo S S, Luh K T

机构信息

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

出版信息

Chest. 2001 Jun;119(6):1961-3. doi: 10.1378/chest.119.6.1961.

DOI:10.1378/chest.119.6.1961
PMID:11399734
Abstract

Severe hemolytic anemia in patients with disseminated tuberculosis is exceedingly rare. We report an episode of Coombs'-positive hemolytic anemia in a previously healthy young man with miliary tuberculosis, resulting in a hemoglobin level of 5 g/dL and an undetectable haptoglobin level. The patient responded well to treatment with antituberculosis drugs, and the results of the direct Coombs' test became negative without the need of blood transfusion or steroid therapy.

摘要

播散性肺结核患者出现严重溶血性贫血极为罕见。我们报告了一例先前健康的年轻粟粒性肺结核患者发生的库姆斯试验阳性溶血性贫血,导致血红蛋白水平降至5g/dL,触珠蛋白水平检测不到。该患者对抗结核药物治疗反应良好,直接库姆斯试验结果转为阴性,无需输血或类固醇治疗。

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