Mumenthaler M S, O'Hara R, Taylor J L, Friedman L, Yesavage J A
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305-5550, USA.
Psychopharmacology (Berl). 2001 May;155(2):198-203. doi: 10.1007/s002130100700.
Studies about whether or not the cognitive performance of women is influenced by changes in levels of sex steroid hormones across the menstrual cycle have produced ambiguous results.
This study tested whether flight simulator performance differs significantly between the menstrual and the luteal phase of the menstrual cycle.
In a within-subjects design, 24 female pilots were tested twice during their menstrual cycle: once during the menstrual and once during the luteal phase. On both test days they performed a 75-min simulator flight in a Frasca 141, a popular pilot training device.
Despite highly significant differences in estradiol (E2) as well as progesterone (P) levels on the 2 test days, and despite excluding subjects with anovulatory cycles from the analyses, there were no significant differences in overall flight performance between the menstrual and luteal phases. We found no significant correlations between E2 or P levels and flight performance.
We found no evidence that the tested menstrual cycle phases and their associated E2 and P levels significantly influence flight simulator performance. We consider these negative findings based on 24 subjects meaningful because previous studies on the influence of menstrual cycle on cognitive performance have not involved complex "real world" tasks such as piloting an aircraft and they obtained inconsistent results.
关于女性的认知表现是否会受到月经周期中性类固醇激素水平变化影响的研究，结果并不明确。
本研究测试了月经周期中月经期和黄体期的飞行模拟器表现是否存在显著差异。
采用受试者内设计，24名女性飞行员在月经周期内接受了两次测试：一次在月经期，一次在黄体期。在这两个测试日，她们都在Frasca 141（一种常用的飞行员训练设备）上进行了75分钟的模拟器飞行。
尽管两个测试日的雌二醇（E2）和孕酮（P）水平存在高度显著差异，并且在分析中排除了无排卵周期的受试者，但月经期和黄体期的总体飞行表现并无显著差异。我们发现E2或P水平与飞行表现之间没有显著相关性。
我们没有发现证据表明所测试的月经周期阶段及其相关的E2和P水平会显著影响飞行模拟器表现。我们认为基于24名受试者得出的这些阴性结果是有意义的，因为之前关于月经周期对认知表现影响的研究并未涉及驾驶飞机等复杂的“现实世界”任务，且结果不一致。
