Alawi F, Freedman P D
Oral and Maxillofacial Pathology, Flushing, NY, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001 Jun;91(6):693-9. doi: 10.1067/moe.2001.115468.
Metastatic calcification is a pathologic condition characterized by deposition of calcified product in otherwise normal tissues as a result of hyperphosphatemia with or without concurrent hypercalcemia. Metastatic calcification presenting clinically as an oral lesion is extremely rare. To date, only 7 cases of metastatic calcification involving the oral soft tissues have been described. This report describes a case of metastatic calcification of the nasal septum presenting as a mass of the anterior maxillary vestibule in a patient with end-stage renal disease. The case reported is only the second example with nasal septum involvement. A brief review of the clinical and histopathologic features of previously reported intraoral cases is also presented.