Verma D K, Thelekkat Y, Bansal S
1 Department of Oral and Maxillofacial Surgery, Surendera Dental College and Research Institute, Rajasthan, India.
Dentomaxillofac Radiol. 2015;44(5):20140023. doi: 10.1259/dmfr.20140023. Epub 2015 Jan 5.
Soft-tissue calcification is always pathological. Metastatic calcification is calcification of soft tissues owing to hyperphosphataemia with or without hypercalcaemia. Metastatic calcification of oral cavity is extremely rare. A case report of metastatic calcification of the floor of the mouth with atypical radiologic and clinical picture is presented here along with a review of earlier reports. A chance finding of the granular oral mucosa on palpation led to a radiographic examination revealing granular calcifications of the floor of the mouth. Blood chemistry and hormone analysis revealed chronic renal failure and hyperparathyroidism. A diagnosis of metastatic calcification secondary to renal failure was made and the treatment was aimed at correcting the renal failure without any intervention for the asymptomatic calcifications. Key differences between the present case and other cases reported in the literature are outlined.
软组织钙化总是病理性的。转移性钙化是指由于高磷血症伴或不伴高钙血症导致的软组织钙化。口腔转移性钙化极为罕见。本文报告一例具有非典型放射学和临床特征的口底转移性钙化病例，并对既往报道进行综述。触诊时偶然发现颗粒状口腔黏膜，影像学检查显示口底有颗粒状钙化。血液生化和激素分析显示慢性肾衰竭和甲状旁腺功能亢进。诊断为肾衰竭继发的转移性钙化，治疗旨在纠正肾衰竭，而不对无症状钙化进行任何干预。文中概述了本病例与文献报道的其他病例之间的关键差异。
