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Cannabinol: a rapidly formed metabolite of delta-1- and delta-6-tetrahydrocannabinol.

作者信息

McCallum N D, Yagen B, Levy S, Mechoulam R

出版信息

Experientia. 1975 May 15;31(5):520-1. doi: 10.1007/BF01932433.

DOI:10.1007/BF01932433
PMID:1140243
Abstract
摘要

相似文献

1
Cannabinol: a rapidly formed metabolite of delta-1- and delta-6-tetrahydrocannabinol.大麻酚：δ-1-和δ-6-四氢大麻酚的一种快速形成的代谢产物。
Experientia. 1975 May 15;31(5):520-1. doi: 10.1007/BF01932433.
2
Distribution studies of (14C)delta-9-tetrahydrocannabinol in mice: effect of vehicle, route of administration, and duration of treatment.
Toxicol Appl Pharmacol. 1975 Nov;34(2):292-300. doi: 10.1016/0041-008x(75)90034-4.
3
6 -hydroxy- 1 -tetrahydrocannabinol synthesis and biological activity.
Science. 1971 Nov 26;174(4012):951-2. doi: 10.1126/science.174.4012.951.
4
Biliary excretion of delta1-tetrahydrocannabinol and its metabolites in the rat.
Biochem Pharmacol. 1974 Apr 1;23(7):1163-72. doi: 10.1016/0006-2952(74)90290-1.
5
Fate of 14C-delta1-THC in rat plasma after intravenous injection and smoking.静脉注射和吸烟后大鼠血浆中14C-δ1-四氢大麻酚的命运
Eur J Pharmacol. 1974 Jan;25(1):1-8. doi: 10.1016/0014-2999(74)90087-9.
6
Metabolism of delta-1-tetrahydrocannabinol by the rat in vivo and in vitro.大鼠体内和体外对δ-1-四氢大麻酚的代谢
Biochem Pharmacol. 1975 Apr 1;24(7):755-62. doi: 10.1016/0006-2952(75)90116-1.
7
Distribution and metabolism in vivo of 14C-tetrahydrocannabinol in the rat.大鼠体内14C-四氢大麻酚的分布与代谢
Eur J Pharmacol. 1974 Jun;27(1):106-19. doi: 10.1016/0014-2999(74)90207-6.
8
Delta9-tetrahydrocannabinol-uptake by rat liver lysosomes.大鼠肝脏溶酶体对Δ9-四氢大麻酚的摄取
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11-hydroxy- 9 -tetrahydrocannabinol: pharmacology, disposition, and metabolism of a major metabolite of marihuana in man.11-羟基-9-四氢大麻酚：大麻在人体内一种主要代谢物的药理学、分布及代谢
Science. 1972 Jul 7;177(4043):62-4. doi: 10.1126/science.177.4043.62.
10
Contribution of the metabolite 7-hydroxy-delta1-tetrahydrocannabinol towards the pharmacological activity of delta 1-tetrahydrocannabinol in mice.代谢物7-羟基-δ1-四氢大麻酚对δ1-四氢大麻酚在小鼠体内药理活性的贡献。
Biochem Pharmacol. 1973 Jan 15;22(2):175-84. doi: 10.1016/0006-2952(73)90271-2.

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The Therapeutic Aspects of the Endocannabinoid System (ECS) for Cancer and their Development: From Nature to Laboratory.内源性大麻素系统（ECS）在癌症治疗中的作用及其发展：从自然到实验室
Curr Pharm Des. 2016;22(12):1756-66. doi: 10.2174/1381612822666151211094901.
2
Cannabidiol and its pharmacokinetic interaction with delta1-tetrahydrocannabinol.
Experientia. 1975 Nov 15;31(11):1268-9. doi: 10.1007/BF01945772.
3
The effect of cannabinol delta1-tetrahydro-cannabinol clearance from the blood.大麻酚δ1-四氢大麻酚从血液中清除的效果。

本文引用的文献

1
[ON THE CHEMICAL CLASSIFICATION OF PLANTS. XXIV. INVESTIGATION OF HASHISH CONSTITUENTS BY THIN-LAYER CHROMATOGRAPHY].[论植物的化学分类。二十四。用薄层色谱法研究大麻成分]
J Chromatogr. 1964 Jan;13:90-8. doi: 10.1016/s0021-9673(01)95077-0.
2
Chemical basis of hashish activity.大麻活性的化学基础。
Science. 1970 Aug 7;169(3945):611-2. doi: 10.1126/science.169.3945.611.
3
Biliary excretion of delta1-tetrahydrocannabinol and its metabolites in the rat.
Biochem Pharmacol. 1974 Apr 1;23(7):1163-72. doi: 10.1016/0006-2952(74)90290-1.
Experientia. 1975 Aug 15;31(8):957-8. doi: 10.1007/BF02358875.
4
Isotope effect studies on the dehydrogenation of delta 1-tetrahydrocannabinol in the rat.大鼠体内δ1-四氢大麻酚脱氢作用的同位素效应研究
Experientia. 1977 Aug 15;33(8):1012-4. doi: 10.1007/BF01945939.
4
A comparison of the pharmacological activity in man of intravenously administered delta9-tetrahydrocannabinol, cannabinol, and cannabidiol.
Experientia. 1973 Nov 15;29(11):1368-9. doi: 10.1007/BF01922823.
5
Structure-activity relationships in man of cannabis constituents, and homologs and metabolites of delta9-tetrahydrocannabinol.
Pharmacology. 1974;11(1):3-11. doi: 10.1159/000136462.
6
The determination of cannabinol levels in the blood and interpretation of their significance.血液中大麻酚水平的测定及其意义的解读。
Pharmacology. 1974;11(1):33-7. doi: 10.1159/000136464.
7
Cannabinol-7-oic acid: a metabolite of delta1-tetrahydrocannabinol in the rhesus monkey.大麻酚-7-酸：恒河猴体内δ1-四氢大麻酚的一种代谢产物。
Res Commun Chem Pathol Pharmacol. 1974 Sep;9(1):201-4.