McEntee M C, Thrall D E
Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis 95616, USA.
Vet Radiol Ultrasound. 2001 May-Jun;42(3):221-5. doi: 10.1111/j.1740-8261.2001.tb00928.x.
Twenty two dogs with an infiltrative lipoma had computed tomographic (CT) images acquired to evaluate the extent of local disease. Ten dogs had undergone at least one cytoreductive surgical procedure (range = 1-3; median = 2) prior to imaging. Twenty dogs had measurable disease on CT images; 2 dogs had diffuse disease at a previous surgical site that could not be measured. Tumor volume (n = 20) ranged from 20 to 5,632 cm3 (median = 345 cm3; mean = 996 cm3). None of the dogs had evidence of bone involvement on the CT images; 2 of the 22 dogs had tumors that did not come into direct contact with osseous structures. All dogs with measurable disease had evidence of a fat opacity mass with variable degrees of muscle infiltration. Eleven of 22 dogs were given intravenous contrast medium prior to image acquisition and there was not evidence of enhancement of the infiltrative lipoma in any dog. Based on CT images, tumors were classified as well-defined in 9 dogs, moderately well-defined in 4, not well-defined in 3 and a mix of well-defined and not well-defined in 6 dogs. Tumors tended to be less well-defined in regions where the infiltrative lipoma interdigitated with normal body fat. It appears CT imaging allows adequate discrimination of tumor with the caveat that differentiation of normal fat from infiltrative lipoma can be problematic.
22只患有浸润性脂肪瘤的犬接受了计算机断层扫描（CT）检查，以评估局部疾病的范围。10只犬在成像前至少接受了一次减瘤手术（范围=1-3次；中位数=2次）。20只犬的CT图像上有可测量的疾病；2只犬在先前手术部位有无法测量的弥漫性疾病。肿瘤体积（n=20）范围为20至5632 cm³（中位数=345 cm³；平均值=996 cm³）。CT图像上没有一只犬有骨受累的证据；22只犬中有2只的肿瘤未与骨结构直接接触。所有有可测量疾病的犬都有脂肪密度肿块的证据，伴有不同程度的肌肉浸润。22只犬中有11只在图像采集前接受了静脉造影剂注射，没有一只犬的浸润性脂肪瘤有强化的证据。根据CT图像，9只犬的肿瘤被分类为边界清晰，4只中等清晰，3只不清晰，6只犬的肿瘤边界清晰与不清晰混合。在浸润性脂肪瘤与正常体脂交错的区域，肿瘤往往边界不那么清晰。看来CT成像能够对肿瘤进行充分鉴别，但需要注意的是，正常脂肪与浸润性脂肪瘤的区分可能存在问题。
