Cermakian N, Sassone-Corsi P
Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS-INSERM-Université Louis Pasteur, 1, Rue Laurent Fries, 67404 Illkirch-Strasbourg, France.
Nat Rev Mol Cell Biol. 2000 Oct;1(1):59-67. doi: 10.1038/35036078.
Living organisms adapt to light-dark rhythmicity using a complex programme based on internal clocks. These circadian clocks, which are regulated by the environment, direct various physiological functions. As the molecular mechanisms that govern clock function are unravelled, we are starting to appreciate simple patterns as well as exquisite layers of regulation.
生物体利用基于内部时钟的复杂程序来适应昼夜节律。这些受环境调节的生物钟指导着各种生理功能。随着控制时钟功能的分子机制被揭示，我们开始认识到简单的模式以及精妙的调节层次。
