共济失调毛细血管扩张症中的一个具有14/14标记染色体的淋巴细胞克隆。
A 14/14 marker chromosome lymphocyte clone in ataxia telangiectasia.
作者信息
Rary J M, Bender M A, Kelly T E
出版信息
J Hered. 1975 Jan-Feb;66(1):33-5. doi: 10.1093/oxfordjournals.jhered.a108569.
Abstract
A lymphocyte clone with a 45, XY karyotype with a 14/14 tandem translocation marker, the frequency of which is time-variable, has been observed in an ataxia telangiectasia patient. Cells with the marker chromotosome were not observed in fibroblasts cultures derived from a skin biopsy, nor was the marker observed in leukocyte cultures from the patient's two affected sibs.
摘要
在一名共济失调毛细血管扩张症患者中观察到一个淋巴细胞克隆，其核型为45, XY，带有一个14/14串联易位标记，该标记的频率随时间变化。在取自皮肤活检的成纤维细胞培养物中未观察到带有标记染色体的细胞，在该患者的两名患病同胞的白细胞培养物中也未观察到该标记。
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