Mukherji S K, Isaacs D L, Creager A, Shockley W, Weissler M, Armao D
Department of Radiology, University of North Carolina School of Medicine, 3324 Old Infirmary CD 7510, Chapel Hill, NC 27599-7510, USA.
AJR Am J Roentgenol. 2001 Jul;177(1):237-43. doi: 10.2214/ajr.177.1.1770237.
The purpose of this study was to determine the diagnostic accuracy of CT in detecting mandibular invasion by squamous cell carcinoma of the oral cavity.
Forty-nine patients who had squamous cell carcinoma of the oral cavity that was clinically fixed to the mandible were treated with mandibulectomy. All patients underwent contrast-enhanced CT (contiguous 3-mm-thick sections) through the primary site before surgery. All studies were reconstructed with bone algorithm. These studies were retrospectively reviewed by a neuroradiologist for evidence of mandibular invasion. The imaging results were compared with the histologic findings in all cases.
CT correctly revealed 25 of 26 cases with mandibular invasion. CT correctly excluded mandibular invasion in 20 of 23 cases without invasion. The diagnostic accuracy of CT for detecting mandibular invasion was as follows: sensitivity, 96%; specificity, 87%; positive predictive value, 89%; and negative predictive value, 95%.
Thin-section (3-mm) CT reconstructed with bone algorithm is an accurate technique to detect mandibular involvement by squamous cell carcinoma of the oral cavity.
本研究的目的是确定CT在检测口腔鳞状细胞癌下颌骨侵犯方面的诊断准确性。
49例临床上与下颌骨固定的口腔鳞状细胞癌患者接受了下颌骨切除术。所有患者在手术前均通过原发部位进行了增强CT扫描（连续3毫米厚的层面）。所有研究均采用骨算法重建。这些研究由一位神经放射科医生进行回顾性审查，以寻找下颌骨侵犯的证据。将所有病例的影像学结果与组织学结果进行比较。
CT正确显示了26例下颌骨侵犯病例中的25例。CT正确排除了23例无侵犯病例中的20例下颌骨侵犯。CT检测下颌骨侵犯的诊断准确性如下：敏感性为96%；特异性为87%；阳性预测值为89%；阴性预测值为95%。
采用骨算法重建的薄层（3毫米）CT是检测口腔鳞状细胞癌下颌骨受累的准确技术。
