Nae Andreea, O'Leary Gerard, Feeley Linda, Fives Cassie, Fitzgerald Brendan, Chiriac Elena, Sheahan Patrick
ENT Department, South Infirmary-Victoria University Hospital, Cork, Ireland.
Department of Pathology, Cork University Hospital, Cork, Ireland.
World J Otorhinolaryngol Head Neck Surg. 2019 Mar 22;5(2):71-75. doi: 10.1016/j.wjorl.2019.02.001. eCollection 2019 Jun.
Oral cavity squamous cell carcinoma (SCC) may present with early invasion of mandibular bone. Preoperative planning of surgery is essential considering patient's postoperative quality of life. Our purpose was to evaluate the efficacy of computer tomography scan (CT) and magnetic resonance imaging (MRI) in detecting mandibular bone involvement in oral SCC.
A retrospective study was conducted on 98 patients with SCC of floor of mouth, lower alveolus and retromolar trigone operated on with curative intent. Preoperative CT and MRI scans were re-reviewed by a consultant radiologist and original histology slides were re-reviewed by 3 pathologists.
Forty-five patients were included in the final study. Combined CT and MRI had a sensitivity of 100% and a specificity of 72%.
The results suggest that combined CT and MRI have diagnostic utility in detecting mandibular invasion by oral cancer, but with a significant false positive rate.
口腔鳞状细胞癌（SCC）可能早期侵犯下颌骨。考虑到患者术后生活质量，术前手术规划至关重要。我们的目的是评估计算机断层扫描（CT）和磁共振成像（MRI）在检测口腔SCC下颌骨受累情况方面的有效性。
对98例接受根治性手术的口底、下牙槽和磨牙后三角SCC患者进行回顾性研究。由一位放射科顾问重新审查术前CT和MRI扫描结果，并由3位病理学家重新审查原始组织学切片。
最终研究纳入45例患者。CT和MRI联合检查的敏感性为100%，特异性为72%。
结果表明，CT和MRI联合检查在检测口腔癌下颌骨侵犯方面具有诊断价值，但假阳性率较高。
