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系统性红斑狼疮患者中抗β2-糖蛋白-1抗体

[Antibodies to beta2-glycoprotein-1 in patients with systemic lupus erythematosus].

作者信息

Borodin A G, Baranov N G, Nasonov E L

出版信息

Klin Med (Mosk). 2001;79(2):49-51.

PMID:11419087
Abstract

Antibodies to beta 2-glycoprotein I (beta 2-GPI) and antibodies to cardiolipin (aCL) were determined by enzyme immunoassay in 58 patients with verified SLE. Elevated level of antibodies to beta 2-GPI was associated with development of antiphospholipid syndrome (APS) and aCL hyperproduction. It is evident that synthesis of antibodies to beta 2-GPI is an additional marker of APS in SLE.

摘要

采用酶免疫分析法对58例确诊的系统性红斑狼疮（SLE）患者检测了抗β2糖蛋白I（β2-GPI）抗体和抗心磷脂（aCL）抗体。抗β2-GPI抗体水平升高与抗磷脂综合征（APS）的发生及aCL的过度产生相关。显然，抗β2-GPI抗体的合成是SLE中APS的一个附加标志物。

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