Cualing H, Schroder L, Perme C
Department of Pathology, University of Cincinnati, Cincinnati, Ohio 45267-0529, USA.
Arch Pathol Lab Med. 2001 Jul;125(7):954-7. doi: 10.5858/2001-125-0954-AGSTAL.
Allergic granulomatosis is a disorder of obscure etiology characterized by infiltration of lymph nodes with histiocytic granulomas and eosinophils. In this report, we describe a case of allergic granulomatosis that is consistent with Churg-Strauss disease limited to lymph nodes. The histologic findings of this patient's lymph nodes demonstrated eosinophilic abscesses and ring-shaped necrotizing and nonnecrotizing granulomas surrounding hyperplastic germinal centers. We report herein a rare type of reactive lymphadenopathy and present its histologic, immunohistochemical, and flow cytometric findings, which may allow its distinction from other lymphadenopathies.
变应性肉芽肿病是一种病因不明的疾病,其特征为组织细胞性肉芽肿和嗜酸性粒细胞浸润淋巴结。在本报告中,我们描述了一例符合局限于淋巴结的Churg-Strauss病的变应性肉芽肿病病例。该患者淋巴结的组织学表现为嗜酸性脓肿以及围绕增生性生发中心的环形坏死性和非坏死性肉芽肿。我们在此报告一种罕见类型的反应性淋巴结病,并展示其组织学、免疫组织化学和流式细胞术检查结果,这些结果可能有助于将其与其他淋巴结病相鉴别。