Liu T H, Consorti E T, Kawashima A, Tamm E P, Kwong K L, Gill B S, Sellin J H, Peden E K, Mercer D W
Department of Surgery, The University of Texas-Houston Medical School and Lyndon B. Johnson General Hospital, Houston, Texas, USA.
Ann Surg. 2001 Jul;234(1):33-40. doi: 10.1097/00000658-200107000-00006.
To assess the utility of triage guidelines for patients with cholelithiasis and suspected choledocholithiasis, incorporating selective use of magnetic resonance cholangiography (MRC) and endoscopic retrograde cholangiopancreatography (ERCP) before laparoscopic cholecystectomy (LC).
ERCP is the most frequently used modality for the diagnosis and resolution of choledocholithiasis before LC. MRC has recently emerged as an accurate, noninvasive modality for the detection of choledocholithiasis. However, useful strategies for implementing this diagnostic modality for patient evaluation before LC have not been investigated.
During a 16-month period, the authors prospectively evaluated all patients before LC using triage guidelines incorporating patient information obtained from clinical evaluation, serum chemistry analysis, and abdominal ultrasonography. Patients were then assigned to one of four groups based on the level of suspicion for choledocholithiasis (group I, extremely high; group 2, high; group 3, moderate; group 4, low). Group 1 patients underwent ERCP and clearance of common bile duct stones; group 2 patients underwent MRC; group 3 patients underwent LC with intraoperative cholangiography; and group 4 patients underwent LC without intraoperative cholangiography.
Choledocholithiasis was detected in 43 of 440 patients (9.8%). The occurrence of choledocholithiasis among patients in the four groups were 92.6% (25/27), 32.4% (12/37), 3.8% (2/52), and 0.9% (3/324) for groups 1, 2, 3, and 4, respectively (P <.001). MRC was used for 8.4% (37/440) of patients. Patient triage resulted in the identification of common bile duct stones during preoperative ERCP in 92.3% (36/39) of the patients. Unsuspected common bile duct stones occurred in six patients (1.4%).
The probability of choledocholithiasis can be accurately assessed based on information obtained during the initial noninvasive evaluation. Stratification of risks for choledocholithiasis facilitates patient management with the most appropriate diagnostic studies and interventions, thereby improving patient care and resource utilization.
评估用于胆结石和疑似胆总管结石患者的分诊指南的效用,该指南纳入了在腹腔镜胆囊切除术(LC)前选择性使用磁共振胰胆管造影(MRC)和内镜逆行胰胆管造影(ERCP)。
ERCP是LC前诊断和解决胆总管结石最常用的方法。MRC最近已成为检测胆总管结石的一种准确、无创的方法。然而,尚未研究在LC前将这种诊断方法用于患者评估的有效策略。
在16个月期间,作者使用分诊指南对所有LC前的患者进行前瞻性评估,该指南纳入了从临床评估、血清化学分析和腹部超声检查中获得的患者信息。然后根据对胆总管结石的怀疑程度将患者分为四组(第1组,极高;第2组,高;第3组,中度;第4组,低)。第1组患者接受ERCP和胆总管结石清除术;第2组患者接受MRC;第3组患者接受LC及术中胆管造影;第4组患者接受LC但不进行术中胆管造影。
440例患者中有43例(9.8%)检测到胆总管结石。四组患者中胆总管结石的发生率分别为第1组92.6%(25/27)、第2组32.4%(12/37)、第3组3.8%(2/52)和第4组0.9%(3/324)(P<.001)。37例(8.4%)患者使用了MRC。患者分诊导致92.3%(36/39)的患者在术前ERCP期间发现胆总管结石。6例患者(1.4%)出现未被怀疑的胆总管结石。
根据初始无创评估期间获得的信息可以准确评估胆总管结石的可能性。对胆总管结石风险进行分层有助于通过最合适的诊断研究和干预措施来管理患者,从而改善患者护理和资源利用。