动脉瘤性蛛网膜下腔出血后的虚弱-情感障碍：可靠性、症状学及与预后的关系
Astheno-emotional disorder after aneurysmal SAH: reliability, symptomatology and relation to outcome.
作者信息
Rödholm M, Starmark J E, Svensson E, Von Essen C
机构信息
Department of Psychiatry, Institute of Clinical Neuroscience, Sahlgrenska University Hospital, Göteborg University, Sweden.
出版信息
Acta Neurol Scand. 2001 Jun;103(6):379-85. doi: 10.1034/j.1600-0404.2001.103006379.x.
OBJECTIVES
Neuropsychiatric symptoms commonly found after aneurysmal SAH are covered in the astheno-emotional disorder (AED) of Lindqvist & Malmgrens diagnostic system for organic psychiatry. This study aims to describe the reliability and symptomatology of AED and its relationship with social outcome.
MATERIAL AND METHODS
Patients referred due to aneurysmal SAH (n=78) were assessed after 1-6 months for AED inter-rater reliability (n=36) and after 12 months for AED severity grade, symptomatology and Glasgow Outcome Scale (GOS) (n=63).
RESULTS
There was no systematic error in diagnosing and grading AED, and the agreement was 85% and 67% respectively (kappa=0.65 and 0.52). Fatigability, concentration difficulties and memory difficulties were the most frequent symptoms of AED. The relationship between AED and "moderate disability" of GOS was highly significant (P<0.00006).
CONCLUSIONS
AED affects social outcome, and can be diagnosed with high reliability even without neuropsychological testing. Use of the AED diagnosis for evaluation of organic mental symptoms is encouraged.
目的
林德奎斯特和马尔姆格伦的器质性精神病诊断系统中的虚弱 - 情感障碍（AED）涵盖了动脉瘤性蛛网膜下腔出血（SAH）后常见的神经精神症状。本研究旨在描述AED的可靠性、症状学及其与社会结局的关系。
材料与方法
因动脉瘤性SAH转诊的患者（n = 78）在1 - 6个月后评估AED的评分者间可靠性（n = 36），在12个月后评估AED严重程度分级、症状学和格拉斯哥预后量表（GOS）（n = 63）。
结果
在诊断和分级AED时没有系统误差，一致性分别为85%和67%（kappa = 0.65和0.52）。易疲劳、注意力集中困难和记忆困难是AED最常见的症状。AED与GOS的“中度残疾”之间的关系高度显著（P < 0.00006）。
结论
AED影响社会结局，即使不进行神经心理学测试也能高度可靠地诊断。鼓励使用AED诊断来评估器质性精神症状。
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