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与青光眼引流植入物相关的晚期眼内炎

Late endophthalmitis associated with glaucoma drainage implants.

作者信息

Gedde S J, Scott I U, Tabandeh H, Luu K K, Budenz D L, Greenfield D S, Flynn H W

机构信息

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida 33136, USA.

出版信息

Ophthalmology. 2001 Jul;108(7):1323-7. doi: 10.1016/s0161-6420(01)00598-x.

Abstract

OBJECTIVE

To report the clinical course of a series of patients who had late endophthalmitis develop after glaucoma drainage implant (GDI) surgery.

DESIGN

Noncomparative, interventional, consecutive case series.

PARTICIPANTS

Four patients were identified with late endophthalmitis associated with Baerveldt glaucoma implants.

METHODS

The medical records of all patients with endophthalmitis associated with a GDI treated at the Bascom Palmer Eye Institute or University of Florida between January 1, 1987 and December 31, 1999 were retrospectively reviewed. Patients with culture-positive endophthalmitis diagnosed more than 1 month after GDI surgery were included in this series.

MAIN OUTCOME MEASURES

Visual acuity and intraocular pressure (IOP).

RESULTS

Late endophthalmitis associated with Baerveldt glaucoma implants developed 7 weeks to 2 years postoperatively. Exposure of the GDI tube was present in all cases. The implant was removed in three of four patients. Visual acuity worsened from preinfection level in two of four cases. IOP was controlled at last follow-up in all patients, although replacement of the explanted GDI was required in one patient.

CONCLUSIONS

Late endophthalmitis may occur after GDI surgery. Exposure of the GDI tube seems to represent a major risk factor for these infections. To prevent this potentially devastating complication, we recommend prophylactic surgical revision with a patch graft in all cases in which there is an exposed GDI tube.

摘要

目的

报告一系列青光眼引流植入物(GDI)手术后发生迟发性眼内炎患者的临床病程。

设计

非对照、干预性、连续病例系列。

参与者

确定4例与Baerveldt青光眼植入物相关的迟发性眼内炎患者。

方法

回顾性分析1987年1月1日至1999年12月31日在Bascom Palmer眼科研究所或佛罗里达大学接受治疗的所有与GDI相关的眼内炎患者的病历。本系列纳入GDI手术后1个月以上诊断为培养阳性眼内炎的患者。

主要观察指标

视力和眼压(IOP)。

结果

与Baerveldt青光眼植入物相关的迟发性眼内炎在术后7周至2年发生。所有病例均存在GDI管外露。4例患者中有3例取出了植入物。4例中有2例视力从感染前水平恶化。所有患者在最后一次随访时眼压得到控制,尽管1例患者需要更换取出的GDI。

结论

GDI手术后可能发生迟发性眼内炎。GDI管外露似乎是这些感染的主要危险因素。为预防这种潜在的破坏性并发症,我们建议在所有GDI管外露的病例中进行预防性手术修复并植入补片。

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