Medina Carlos A, Butler Michelle R, Deobhakta Avnish A, Banitt Michael R, Albini Thomas A, Smiddy William E, Berrocal Audina M, Gedde Steven J, Flynn Harry W
Ophthalmic Surg Lasers Imaging Retina. 2016 Jun 1;47(6):563-9. doi: 10.3928/23258160-20160601-08.
To identify the clinical features, organisms, and treatment outcomes in patients with endophthalmitis associated with glaucoma drainage implants.
A retrospective noncomparative case series.
Of the 13 patients, exposure occurred in eight eyes, including exposure of the tube in four eyes, exposure of the patch graft in three eyes, and exposure of the plate in one eye. In the remaining five eyes, either recent implant placement or conjunctival revision occurred. The most common organism was Staphylococcus epidermidis (five eyes). Intravitreal antibiotics were administered in all eyes, with the exception of one eye (primary evisceration). Removal of the implant was performed in six eyes and evisceration or enucleation was performed in three eyes. Median pre-infection visual acuity was 20/80 (range: 20/30 to hand motion). Visual acuity at last follow-up was no light perception (five eyes), light perception (two eyes), hand motion (one eye), and better than or equal to 20/200 (five eyes).
Clinical features associated with endophthalmitis include implant exposure and a history of recent surgery. Staphylococcus epidermidis was the most common isolate. Although removal of the implant was performed in many patients, successful treatment was accomplished in some patients without removal. Visual outcomes were generally poor. [Ophthalmic Surg Lasers Imaging Retina. 2016;47:563-569.].
明确与青光眼引流植入物相关的眼内炎患者的临床特征、病原体及治疗结果。
一项回顾性非对照病例系列研究。
13例患者中，8只眼发生植入物暴露，其中4只眼引流管暴露，3只眼补片移植片暴露，1只眼引流板暴露。其余5只眼为近期植入或结膜修补。最常见的病原体是表皮葡萄球菌（5只眼）。除1只眼（一期眼内容剜除术）外，所有眼均给予玻璃体内注射抗生素。6只眼取出植入物，3只眼行眼内容剜除术或眼球摘除术。感染前的中位视力为20/80（范围：20/30至手动）。末次随访时的视力为无光感（5只眼）、光感（2只眼）、手动（1只眼）以及优于或等于20/200（5只眼）。
与眼内炎相关的临床特征包括植入物暴露和近期手术史。表皮葡萄球菌是最常见的分离病原体。尽管许多患者取出了植入物，但部分未取出植入物的患者治疗成功。总体视力预后较差。[《眼科手术、激光与视网膜影像》。2016年；47:563 - 569。]
