Tu J V, Austin P C, Chan B T
Institute for Clinical Evaluative Sciences, G-106, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5.
JAMA. 2001 Jun 27;285(24):3116-22. doi: 10.1001/jama.285.24.3116.
Acute myocardial infarction (AMI) is a common condition that is treated by physicians with varying levels of clinical experience, but whether the level of experience affects outcome remains uncertain.
To evaluate the relationship between the average annual volume of cases treated by admitting physicians and mortality after AMI.
DESIGN, SETTING, AND PATIENTS: Retrospective cohort study using linked administrative databases containing patient admission information for 98 194 patients treated by 5374 physicians between April 1, 1992, and March 31, 1998, in Ontario, Canada.
Mortality risk rates for 30 days and 1 year post-AMI, adjusted by physician volume and patient, physician, and hospital characteristics.
The 30-day mortality rate was 13.5% and the 1-year mortality rate was 21.8%. A strong inverse relationship between the average annual volume of AMI cases treated by the admitting physician and mortality after an AMI was observed. The 30-day risk-adjusted mortality rate was 15.3% for physicians who treated 5 or fewer AMI cases per year (lowest quartile) compared with 11.8% for physicians who treated more than 24 AMI cases annually (highest quartile; P<.001). The 1-year risk-adjusted mortality rate was 24.2% for physicians who treated 5 or fewer AMI cases per year (lowest quartile) compared with 19.6% for physicians who treated more than 24 AMI cases annually (highest quartile; P<.001).
Patients with AMI who are treated by high-volume admitting physicians are more likely to survive at 30 days and 1 year.
急性心肌梗死(AMI)是一种常见疾病,不同临床经验水平的医生都可对其进行治疗,但经验水平是否会影响治疗结果仍不确定。
评估收治医生每年平均治疗病例数与急性心肌梗死后死亡率之间的关系。
设计、地点和患者:采用回顾性队列研究,使用关联的行政数据库,这些数据库包含了1992年4月1日至1998年3月31日期间加拿大安大略省5374名医生治疗的98194例患者的入院信息。
急性心肌梗死后30天和1年的死亡风险率,根据医生治疗量以及患者、医生和医院特征进行调整。
30天死亡率为13.5%,1年死亡率为21.8%。观察到收治医生每年平均治疗的急性心肌梗死病例数与急性心肌梗死后死亡率之间存在强烈的负相关关系。每年治疗5例或更少急性心肌梗死病例的医生(最低四分位数),其30天风险调整后死亡率为15.3%,而每年治疗超过24例急性心肌梗死病例的医生(最高四分位数),其30天风险调整后死亡率为11.8%(P<0.001)。每年治疗5例或更少急性心肌梗死病例的医生(最低四分位数),其1年风险调整后死亡率为24.2%,而每年治疗超过24例急性心肌梗死病例的医生(最高四分位数),其1年风险调整后死亡率为19.6%(P<0.001)。
由大量收治医生治疗的急性心肌梗死患者在30天和1年时存活的可能性更大。