Porter T L, Eastman M P, Bain E, Begay S
Northern Arizona University, Department of Physics and Astronomy, Flagstaff, AZ 86011, USA.
Biophys Chem. 2001 Jul 2;91(2):115-24. doi: 10.1016/s0301-4622(01)00159-4.
We have investigated the synthesis of oligopeptides containing glycine and tyrosine in the presence of the clay minerals montmorillonite (non-exchanged, SAz-1) and Cu(2+) exchanged hectorite. In both cases, homopolymers of the two amino acids are formed, as are mixed peptides. In the case of Cu(2+) hectorite, mixed oligopeptides up to trimers are detected in small amounts. For montmorillonite, heterogeneous oligopeptides up to hexamers are detected. Our experiments indicate montmorillonite is more effective in promoting oligopeptide formation than Cu(2+) hectorite. Analysis of the oligopeptide sequences formed on the montmorillonite surfaces indicates preferential synthesis of certain Gly-Tyr sequences over others.
我们研究了在粘土矿物蒙脱石（未交换，SAz - 1）和铜（II）交换的锂皂石存在下，含有甘氨酸和酪氨酸的寡肽的合成。在这两种情况下，都会形成这两种氨基酸的均聚物以及混合肽。在铜（II）锂皂石的情况下，检测到少量直至三聚体的混合寡肽。对于蒙脱石，检测到直至六聚体的异质寡肽。我们的实验表明，蒙脱石在促进寡肽形成方面比铜（II）锂皂石更有效。对蒙脱石表面形成的寡肽序列的分析表明，某些甘氨酸 - 酪氨酸序列比其他序列更易合成。
