Berrebi A, Parant O, Ferval F, Thene M, Ayoubi J M, Connan L, Belon P
Fédération de Gynécologie-Obstétrique, Service de Pharmacie, CHU La Grave, 31052 Toulouse Cedex, France.
J Gynecol Obstet Biol Reprod (Paris). 2001 Jun;30(4):353-7.
Dopaminergic agonists, such as Parlodel((R)), are now widely used to inhibit lactation. However, some countries, such as the United States, no longer use these drugs in this indication because of their sometimes serious adverse effects. In this context, the authors tested a homeopathic treatment designed for parturients unable or not wanting to breastfeed. The APIS MELLIFICA 9 CH and BRYONIA 9 CH combination was chosen for its anti-inflammatory and analgesic effects. 71 patients were included in this double-blind placebo-controlled study. All received basic treatment comprising naproxen and fluid restriction. A significant improvement of lactation pain (main criterion of the study) was observed in parturients treated with homeopathy (p<0.02 on D2 and p<0.01 on D4). A similar effect (p<0.05 on D4) was observed for breast tension and spontaneous milk flow. No significant difference was observed for the other criteria of the study. The homeopathic combination studied was therefore effective on the pain of lactation and should be integrated into the therapeutic armamentarium.
多巴胺能激动剂,如溴隐亭(Parlodel((R))),如今被广泛用于抑制泌乳。然而,一些国家,如美国,由于这些药物有时会产生严重的不良反应,已不再将其用于此适应症。在此背景下,作者对一种为无法或不愿母乳喂养的产妇设计的顺势疗法进行了测试。选择蜜蜂花9CH和泻根9CH的组合是因其具有抗炎和止痛作用。71名患者被纳入这项双盲安慰剂对照研究。所有患者均接受包括萘普生和液体限制在内的基础治疗。接受顺势疗法治疗的产妇泌乳疼痛(该研究的主要标准)有显著改善(第2天p<0.02,第4天p<0.01)。乳房张力和自然泌乳量也观察到类似效果(第4天p<0.05)。该研究的其他标准未观察到显著差异。因此,所研究的顺势疗法组合对泌乳疼痛有效,应纳入治疗手段中。