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[与细胞溶解性肝炎相关的脑脊髓膜李斯特菌病。塞内加尔首例病例报告]

[Cerebromeningeal listeriosis associated with a cytolytic hepatitis. First case report in Senegal].

作者信息

Camara P, Petrognani R, Aubron C, Colbachini P, Ferret C, Hovette P

机构信息

Service de Médecine Interne et de Pathologies Infectieuses, BP 3006, Hôpital Principal, Dakar, Sénégal.

出版信息

Med Trop (Mars). 2000;60(4):357-60.

Abstract

Hepatitis due to Listeria monocytogenes is uncommon in adults. This report describes the first case observed in Senegal. The patient was a 73-year old man presenting listeria-related hepatitis presumably secondary to low-grade meningeal encephalitis. Treatment using ampicillin was unsuccessful and the patient died four days after hospitalization. The authors note that the incidence of adult listeriosis has risen constantly for the past twenty years in relation with alcohol abuse, cirrhosis, diabetes, kidney insufficiency, cancer, AIDS, and organ transplantation. However no predisposing factors were observed in the present case.

摘要

由单核细胞增生李斯特菌引起的肝炎在成年人中并不常见。本报告描述了在塞内加尔观察到的首例病例。患者为一名73岁男性,表现为可能继发于轻度脑膜脑炎的李斯特菌相关性肝炎。使用氨苄西林治疗未成功,患者在住院四天后死亡。作者指出,在过去二十年中,与酗酒、肝硬化、糖尿病、肾功能不全、癌症、艾滋病和器官移植相关,成人李斯特菌病的发病率持续上升。然而,在本病例中未观察到诱发因素。

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