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[用于主动脉硬化鉴别诊断的主动脉血流速度的同位素血管造影测量]

[Isotope-angiographic measurement of aortic flow velocity for differential diagnosis of aortic sclerosis].

作者信息

Schicha H, Becker V, Vyska K, Feinendegen L E

出版信息

Nucl Med (Stuttg). 1975 Mar 31;14(1):12-21.

PMID:1144052
Abstract

The speed of flow between aortic arch and abdominal aorta was determined from the corresponding minimal transit time (MTT) measured with 113m-In-DTPA and the Fucks-Knipping gamma camera. A total of 144 individuals was examined: 62 normal persons, 34 patients with cardiac insufficiency; 31 patients with hyperkinetic syndrome (effort syndrome and hyperthyroidism) and 17 patients with isolated aortic sclerosis without impairment of cardiac function. In all individual groups there was a highly significant correlation between speed of flow and heart rate. For a given heart rate speed of flow was diminished in cases of cardiac insufficiency and aortic sclerosis; it was accelerated in patients with hyperkinetic syndrome. By plotting the speed of flow through the aorta, normalized to an arbitary heart rate, against the corresponding MTT, also normalized to the same heart rate, the presence of aortic sclerosis could be differentially recognized in 14 of the 17 patients with this disease.

摘要

利用¹¹³m - 铟 - 二乙三胺五乙酸(¹¹³m - In - DTPA)和福克斯 - 克尼平γ相机测量相应的最小通过时间(MTT),从而测定主动脉弓与腹主动脉之间的血流速度。共检查了144人:62名正常人、34名心力衰竭患者、31名高动力综合征患者(心脏神经官能症和甲状腺功能亢进症)以及17名孤立性主动脉硬化且心功能未受损的患者。在所有个体组中,血流速度与心率之间均存在高度显著的相关性。对于给定的心率,心力衰竭和主动脉硬化患者的血流速度降低;高动力综合征患者的血流速度加快。通过绘制将主动脉血流速度标准化到任意心率后与同样标准化到该心率的相应MTT的关系图,在17例患有这种疾病的患者中,有14例能够鉴别出主动脉硬化的存在。

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