du Toit R, Situ P, Simpson T, Fonn D
Centre for Contact Lens Research, University of Waterloo, Ontario, Canada.
Optom Vis Sci. 2001 Jun;78(6):455-62. doi: 10.1097/00006324-200106000-00020.
To assess the tear film, ocular surfaces, and symptoms of ocular discomfort in a presbyopic population before and after contact lens wear.
A total of 150 presbyopes (49% were previous soft contact lens wearers) participated in a clinical trial in which they wore either monovision (single vision Acuvue lenses) or Acuvue Bifocal contact lenses. Clinical measurements of tear film, biomicroscopy, and corneal sensitivity as well as subjective ratings using the Dry Eye Questionnaire were collected at the initial visit and repeated after 6 months. Comparisons were made between age groups (40 to 51 years and 52 to 71 years) and genders before and after contact lens wear. Associations between objective and subjective tests were sought.
After 6 months of contact lens wear, clinical signs had worsened by less than one-half of a grade, and tear break up time (TBUT) worsened by 3 s. Only TBUT was lower for the older age group. Females had less bulbar hyperemia, more sensitive eyes, more lissamine green staining, and lower TBUT and phenol red thread measurements (all p < 0.04). Twenty-eight percent experienced dryness before contact lens wear, but this figure increased to 68% when wearing contact lenses. There were no age differences, but almost twice as many females as males reported dryness. Reporting symptoms of dryness was associated with gender, corneal sensitivity, and type of corneal staining.
These results provide a representation of the ocular surface condition and symptoms of ocular discomfort in the middle-aged population and seem similar to reports of younger populations. Wearing contact lenses seems to influence dry eye symptoms more than age or gender. Therefore, presbyopes should not be excluded from consideration for contact lens fitting.
评估老视人群佩戴隐形眼镜前后的泪膜、眼表及眼部不适症状。
共有150名老视者(49%曾佩戴过软性隐形眼镜)参与一项临床试验,他们分别佩戴单眼视力矫正(单焦点安视优镜片)或安视优双焦点隐形眼镜。在初次就诊时收集泪膜、生物显微镜检查、角膜敏感性的临床测量数据以及使用干眼问卷的主观评分,并在6个月后重复收集。比较佩戴隐形眼镜前后不同年龄组(40至51岁和52至71岁)及不同性别的情况。探寻客观测试与主观测试之间的关联。
佩戴隐形眼镜6个月后,临床体征恶化程度不到半个等级,泪膜破裂时间(TBUT)恶化3秒。仅老年组的TBUT较低。女性的球结膜充血较少、眼睛更敏感、丽丝胺绿染色更多,且TBUT和酚红棉线测量值较低(所有p<0.04)。28%的人在佩戴隐形眼镜前有干眼症状,但佩戴隐形眼镜时这一比例增至68%。不存在年龄差异,但报告有干眼症状的女性人数几乎是男性的两倍。报告干眼症状与性别、角膜敏感性及角膜染色类型有关。
这些结果反映了中年人群的眼表状况及眼部不适症状,似乎与年轻人群的报告相似。佩戴隐形眼镜似乎比年龄或性别对干眼症状的影响更大。因此,不应将老视者排除在隐形眼镜验配的考虑范围之外。