Pérez J A, Padilla J, Rodríguez M A, Cura S, Sánchez S, Cutillas M J, Sanz J
Servicio de Anestesiología y Reanimación, Hospital General Universitario José M. Morales Meseguer, Murcia, Spain.
Rev Esp Anestesiol Reanim. 2001 Jun-Jul;48(6):288-91.
A 36-year-old woman with beta thalassemia intermedia suffered a hemolytic crisis secondary to Epstein-Barr virus infection. She was given a transfusion of phenotypically compatible blood. However, severe hemolysis persisted (with hemoglobin levels around 4 g/dl) in spite of gamma globulin and corticosteroid administration. Emergency therapeutic splenectomy was performed. We discuss intraoperative management in situations of severe anemia, concluding that it is possible to survive significant decreases in hemoglobin concentration with cardiocirculatory reserve and respiration intact, maintaining normal volume.
一名36岁的中间型β地中海贫血女性患者因感染爱泼斯坦-巴尔病毒而引发溶血性危机。她接受了表型匹配的输血。然而，尽管给予了γ球蛋白和皮质类固醇治疗，严重溶血仍持续存在（血红蛋白水平约为4 g/dl）。遂进行了急诊治疗性脾切除术。我们讨论了严重贫血情况下的术中管理，得出结论：在心脏循环储备和呼吸功能完好、维持正常血容量的情况下，血红蛋白浓度显著下降时仍有可能存活。
