Sibai A M, Fletcher A, Armenian H K
Department of Epidemiology and Biostatistics, Faculty of Health Sciences, American University of Beirut, Beirut, Lebanon.
Am J Epidemiol. 2001 Jul 15;154(2):128-37. doi: 10.1093/aje/154.2.128.
The authors investigated the relation between exposure to wartime events and cardiovascular disease (CVD) and all-cause mortality in Lebanon, which recently underwent a 16-year civil war. The study population comprised a representative cohort (n = 1,786) of middle-aged and older men and women who, in 1983, participated in a community-based health interview survey. In 1993, the authors traced 87.7 % of the original cohort (n = 1,567) and assessed their vital status, exposure to war-related events, and, in case they had died, cause of death. War experiences were aggregated into different clusters according to type of exposure, realm affected (human vs. property losses), and person central to the event. Women, but not men, had a significantly elevated CVD mortality risk for exposures to human traumas that occurred to them (rate ratio = 3.37, 95% confidence interval: 1.41, 8.05) or their families (rate ratio = 1.45, 95% confidence interval: 1.20, 1.74). Exposure to property losses and work-related problems carried a greater mortality risk for men, particularly those with lower levels of education, than for women. Subjects displaced during the war had a significantly higher risk for CVD and total mortality. These results suggest that, during prolonged wars, different elements of exposures have a long-term impact on mortality, with effects varying by gender and socioeconomic resources.
作者调查了黎巴嫩经历了16年内战的情况下,战时经历与心血管疾病(CVD)及全因死亡率之间的关系。研究人群包括一个具有代表性的队列(n = 1786),由中年及老年男性和女性组成,他们于1983年参加了一项基于社区的健康访谈调查。1993年,作者追踪了原队列中的87.7%(n = 1567),评估了他们的生命状态、与战争相关事件的暴露情况,以及如果他们已经死亡,其死亡原因。战争经历根据暴露类型、受影响的领域(人员伤亡与财产损失)以及事件核心人物被汇总成不同的类别。女性而非男性,在经历自身(率比 = 3.37,95%置信区间:1.41,8.05)或其家人遭受的人身创伤时,心血管疾病死亡率风险显著升高(率比 = 1.45,95%置信区间:1.20,1.74)。与女性相比,男性尤其是受教育程度较低的男性,遭受财产损失和与工作相关问题时的死亡风险更高。战争期间流离失所的受试者患心血管疾病和总死亡率的风险显著更高。这些结果表明,在长期战争期间,不同的暴露因素对死亡率有长期影响,且影响因性别和社会经济资源而异。