Bertolotti C, Deplano V, Fuseri J, Dupouy P
IRPHE UMR no 6594/ESM2 Laboratoire de Biomécanique Cardiovasculaire Technopôle de Château Gombert, 13451 Cedex 20, Marseille, France.
J Biomech. 2001 Aug;34(8):1049-64. doi: 10.1016/s0021-9290(01)00027-6.
By means of both experimental and finite element methods, we simulated three-dimensional unsteady flows through coronary bypass anastomosis. The host artery includes a stenosis shape located at two different distances of grafting. The inflow rates are issued from in vivo measurements in patients who had undergone coronary bypass surgery a few days before. We provide a comparison between experimental and numerical velocity profiles coupled with the numerical analysis of spatial and temporal wall shear stress evolution. The interaction between the graft and coronary flows has been demonstrated. The phase inflow difference can partly be responsible for specific flow phenomena: jet deflection towards a preferential wall or feedback phenomenon that causes the flapping of the post-stenotic jet during the cardiac cycle. In conclusion, we showed the sensitivity of these typical flows to distance of grafting, inflows waveforms but also to their phase difference.
通过实验和有限元方法，我们模拟了通过冠状动脉搭桥吻合术的三维非定常流动。宿主动脉包括位于两个不同移植距离处的狭窄形状。流入速率来自几天前接受冠状动脉搭桥手术的患者的体内测量。我们提供了实验和数值速度剖面之间的比较，以及空间和时间壁面剪应力演变的数值分析。已证明移植物与冠状动脉血流之间的相互作用。相位流入差异可能部分导致特定的流动现象：射流向优先壁面的偏转或反馈现象，该现象在心动周期中导致狭窄后射流的摆动。总之，我们展示了这些典型流动对移植距离、流入波形及其相位差的敏感性。
