Puzanowska-Tarasiewicz H, Kuźmicka L, Kleszczewska E
Institute of Chemistry, University of Białystok, Poland.
J Pharm Biomed Anal. 2001 Aug;26(1):1-5. doi: 10.1016/s0731-7085(00)00598-7.
Reinecke salt and alizarin S have been tested as reagents for the determination of promazine. They react in neutral and acidic media with promazine forming a reddish and brown crystalline compounds. The compounds are sparingly soluble in water but fairly soluble in acetone and methanol. The quantitative extraction of compound of promazine with alizarin S has been used for the extractive spectrophotometric determination of promazine. Formation of promazine ion-association complex with Reinecke salt has been applied for indirect determination of low concentrations of promazine by AAS measurement of the chromium content of the reineckate counter - anion.