Landrault N, Poucheret P, Ravel P, Gasc F, Cros G, Teissedre P L
Département d'Oenologie and Laboratoire de Pharmacologie, Faculté de Pharmacie, Université de Montpellier I, Avenue Charles Flahault, 34060 Montpellier Cedex 2, France.
J Agric Food Chem. 2001 Jul;49(7):3341-8. doi: 10.1021/jf010128f.
Phenolics from grapes and wines can play a role against oxidation and development of atherosclerosis. Levels of phenolics, major catechins [(+)-catechin, (-)-epicatechin, procyanidin dimers B1, B2, B3, and B4], phenolic acids (gallic acid and caffeic acid), caftaric acid, malvidin-3-glucoside, peonidin-3-glucoside, and cyanidin-3-glucoside were quantified by HPLC with UV detection for 54 French varietal commercial wines taken from southern France to study the antioxidant capacity and the daily dietary intake of these compounds for the French population. The highest antioxidant capacity was obtained with red wines and ranged from 12.8 mmol/L (Grenache) to 25.2 mmol/L (Pinot Noir). For white wines, Chardonnay enriched in phenolics by special wine-making was found to have an antioxidant capacity of 13.8 mmol/L, comparable to red wine values. For red wines classified by vintages (1996-1999) antioxidant capacities were approximately 20 mmol/L and then decreased to 13.4 mmol/L for vintages 1995-1991. Sweet white wines have 1.7 times more antioxidant capacity (3.2 mmol/L) than dry white wines (1.91 mmol/L). On the basis of a still significant French wine consumption of 180 mL/day/person, the current daily intake of catechins (monomers and dimers B1, B2, B3, and B4) averaged 5 (dry white wine), 4.36 (sweet white wines), 7.70 (rosé wines), 31.98 (red wines), and 66.94 (dry white wine enriched in phenolic) mg/day/resident for the French population. Red wine, and particularly Pinot Noir, Egiodola, Syrah, Cabernet Sauvignon, and Merlot varieties, or Chardonnay enriched in phenolics during wine-making for white varieties contribute to a very significant catechin dietary intake.
葡萄和葡萄酒中的酚类物质有助于对抗氧化作用和动脉粥样硬化的发展。采用高效液相色谱法(HPLC)结合紫外检测,对54种来自法国南部的法国品种商业葡萄酒中的酚类物质水平进行了定量分析,这些酚类物质包括主要的儿茶素[(+)-儿茶素、(-)-表儿茶素、原花青素二聚体B1、B2、B3和B4]、酚酸(没食子酸和咖啡酸)、咖啡酰酒石酸、矢车菊素-3-葡萄糖苷、芍药素-3-葡萄糖苷和花青素-3-葡萄糖苷,以研究这些化合物对法国人群的抗氧化能力和每日膳食摄入量。红葡萄酒的抗氧化能力最高,范围从12.8毫摩尔/升(歌海娜)到25.2毫摩尔/升(黑皮诺)。对于白葡萄酒,通过特殊酿酒工艺富含酚类物质的霞多丽葡萄酒的抗氧化能力为13.8毫摩尔/升,与红葡萄酒的值相当。对于按年份分类的红葡萄酒(1996 - 1999年),抗氧化能力约为20毫摩尔/升,然后在1995 - 1991年的年份中降至13.4毫摩尔/升。甜白葡萄酒的抗氧化能力(3.2毫摩尔/升)是干白葡萄酒(1.91毫摩尔/升)的1.7倍。基于法国人每人每天仍有180毫升的显著葡萄酒消费量,法国人群目前儿茶素(单体和二聚体B1、B2、B3和B4)的每日摄入量平均为5(干白葡萄酒)、4.36(甜白葡萄酒)、7.70(桃红葡萄酒)、31.98(红葡萄酒)和66.94(富含酚类物质的干白葡萄酒)毫克/天/居民。红葡萄酒,特别是黑皮诺、埃吉奥多拉、西拉、赤霞珠和梅洛品种,或者白葡萄酒品种中在酿酒过程中富含酚类物质的霞多丽,对儿茶素的膳食摄入量有非常显著的贡献。