Gurelik G, Safak N, Koksal M, Bilgihan K, Hasanreisoglu B
Gazi University, Medical Faculty, Department of Ophthalmology, Ankara, Turkey.
Int Ophthalmol. 1999;23(3):131-5. doi: 10.1023/a:1010652521578.
To assess acute corneal decompensation after silicone oil removal in some aphakic eyes with clear corneas whose anterior chambers were completely filled with silicone oil for a considerable period of time.
Eight eyes of 8 patients who underwent vitrectomy and intraocular silicone oil injection were studied. All the eyes were aphakic and anterior chambers were completely filled with silicone oil. In all eyes, corneas were clear and no corneal finding indicating keratopathy was detected by slit-lamp microscopy before silicone oil removal. The mean silicone oil removal time was 4 months (range 2-7 months). A specular microscope was used for the evaluation of corneal endothelial changes and corneal pachometry was performed to observe corneal changes before and after the silicone oil removal in 5 eyes besides slit-lamp microscopy. The follow up period after silicone oil removal was 2-12 months (mean 6 months).
In all eyes severe corneal stromal edema and clouding was detected in the first day following silicone oil removal. Increased corneal thickness was seen in all eyes. Decreased (at or below critical levels) corneal cell density was detected by specular microscopy before and after silicone oil removal. No significant improvement was observed during the follow up period.
Eyes whose anterior chambers completely filled with silicone oil could be evaluated as clear corneas by slit lamp microscopy despite severe endothelial damage. We recommend that eyes with silicone oil in the anterior chambers should be monitored by a combination of slit-lamp microscopic examination and specular microscopy to determine the relative corneal endothelial tolerance to the silicone oil and endothelial damage. Early removal of the silicone oil can be considered when the retinal adhesion allows.
评估部分无前房晶状体且角膜透明、前房在相当长一段时间内完全充满硅油的无晶状体眼中硅油取出后的急性角膜失代偿情况。
对8例行玻璃体切除术及眼内硅油注射的患者的8只眼进行研究。所有眼睛均为无晶状体眼,前房完全充满硅油。在所有眼中,角膜透明,在硅油取出前通过裂隙灯显微镜检查未发现提示角膜病变的角膜表现。硅油取出的平均时间为4个月(范围2 - 7个月)。除裂隙灯显微镜检查外,还使用了镜面显微镜评估角膜内皮变化,并对5只眼进行了角膜测厚,以观察硅油取出前后的角膜变化。硅油取出后的随访期为2 - 12个月(平均6个月)。
在所有眼中,硅油取出后的第一天均检测到严重的角膜基质水肿和混浊。所有眼睛均可见角膜厚度增加。通过镜面显微镜检查发现,硅油取出前后角膜细胞密度均降低(达到或低于临界水平)。随访期间未观察到明显改善。
尽管存在严重的内皮损伤,但前房完全充满硅油的眼睛通过裂隙灯显微镜检查仍可被评估为角膜透明。我们建议,对于前房中有硅油的眼睛,应结合裂隙灯显微镜检查和镜面显微镜检查进行监测,以确定角膜内皮对硅油的相对耐受性和内皮损伤情况。当视网膜粘连允许时,可考虑尽早取出硅油。