年龄对孵育大鼠睾丸形成5α-雄甾二醇和7α-羟基睾酮的影响。
Influence of age on the formation of 5alpha-androstanediol and 7alpha-hydroxy-testosterone by incubated rat testes.
作者信息
Lacroix E, Eechaute W, Leusen I
出版信息
Steroids. 1975 May;25(5):649-61. doi: 10.1016/0039-128x(75)90019-7.
PMID:1145683
Abstract
Testes from rats of different ages were indubated with or without tritiated testosterone. The exogenously-added or endogenously-produced testosterone is mainly metabolized to 7alpha-hydroxylated testosterone in adult animals, and to 5alpha-reduced metabolites (especially 5alpha-androstanediol) in immature animals.
摘要
将来自不同年龄大鼠的睾丸在有或没有氚化睾酮的情况下进行孵育。在成年动物中，外源性添加的或内源性产生的睾酮主要代谢为7α-羟基化睾酮，而在未成熟动物中则代谢为5α-还原代谢物（尤其是5α-雄甾二醇）。
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