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迷走神经切断术对犊牛皱胃的影响:放射照相术和蛋白基因产物9.5免疫组织化学

The effects of vagotomy on the abomasum in calves: radiography and protein gene product 9.5 immunohistochemistry.

作者信息

Soehartono R H, Yamada H, Yamagishi N, Kitamura N, Taguchi K

机构信息

Department of Veterinary Surgery, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Japan.

出版信息

J Vet Med Sci. 2001 Jun;63(6):671-4. doi: 10.1292/jvms.63.671.

DOI:10.1292/jvms.63.671
PMID:11459015
Abstract

Abomasal disorders of calves with total vagotomy, operated on at 1 week old, were investigated with radiography and protein gene product (PGP) 9.5 immunohistochemistry. Radiographic findings indicated abomasal atony with dilatation in all calves 2 weeks after vagotomy, while 4 weeks after vagotomy abomasal dilatation was detected in 2 calves and another 2 calves showed dilatation and impaction. The densities of PGP 9.5-immunoreactive nerves in the tunica muscularis decreased significantly in the corpus region of the greater curvature 2 weeks after vagotomy and in the pyloric region of the lesser curvature 4 weeks after vagotomy, and it was at its lowest 4 weeks after vagotomy in all regions examined. In conclusion, abomasal dilatation and/or impaction in vagotomized calves confirmed by radiography were related with a decreased frequency of nerves in the tunica muscularis of the abomasum.

摘要

对1周龄时接受完全迷走神经切断术的犊牛的皱胃疾病进行了影像学和蛋白质基因产物(PGP)9.5免疫组织化学研究。影像学结果显示,迷走神经切断术后2周,所有犊牛均出现皱胃弛缓伴扩张,而迷走神经切断术后4周,2头犊牛出现皱胃扩张,另外2头犊牛出现扩张和阻塞。迷走神经切断术后2周,大弯侧体部肌层中PGP 9.5免疫反应性神经的密度显著降低,迷走神经切断术后4周,小弯侧幽门区域的密度显著降低,且在所有检查区域中,迷走神经切断术后4周时密度最低。总之,影像学证实的迷走神经切断术犊牛的皱胃扩张和/或阻塞与皱胃肌层神经频率降低有关。

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