The subcellular localization of labelled tyrosine in the vitelline cells of Schistosoma mansoni.

Autoradiographic studies at light and electron microscope level showed that tritiated tyrosine injected into the peritoneal cavity of infected mice localised in the cells of adult Schistosoma mansoni within one hour. The amino acid was avidly taken up by vitelline cells compared to other tissues. Subcellular localization was in the granular endoplasmic reticulum and in the vitelline droplets. The label was also present in the tissues of the tegument and gut but the route of entry into the parasite was not determined.