体外培养的曼氏血吸虫雄虫和雌虫对[4-14C]胆固醇的摄取、定位及转运

The uptake, localization and transfer of [4-14C]cholesterol in Schistosoma mansoni males and females maintained in vitro.

作者信息

Haseeb M A, Eveland L K, Fried B

出版信息

Comp Biochem Physiol A Comp Physiol. 1985;82(2):421-3. doi: 10.1016/0300-9629(85)90877-1.

Abstract

Schistosoma mansoni male and female adults incorporated [4-14C]cholesterol in vitro. Males incorporated about three times more cholesterol than females. The major sites of cholesterol deposition in males were the tegument and parenchyma. The tegument and vitelline glands were the primary sites of cholesterol accumulation in females. In males, dorsal tegument showed greater cholesterol uptake than ventral tegument. Radiolabelled males and females transferred cholesterol to unlabelled members of the opposite sex.

摘要

曼氏血吸虫成虫在体外摄取[4-¹⁴C]胆固醇。雄虫摄取的胆固醇量约为雌虫的三倍。雄虫中胆固醇沉积的主要部位是体表和实质组织。体表和卵黄腺是雌虫中胆固醇积累的主要部位。在雄虫中，背侧体表比腹侧体表摄取更多的胆固醇。用放射性标记的雄虫和雌虫将胆固醇转移给未标记的异性个体。