Charsley M M, Abram S E
Albuquerque Veterans Administration Hospital, Albuquerque, New Mexico, USA.
Reg Anesth Pain Med. 2001 Jul-Aug;26(4):301-5. doi: 10.1053/rapm.2001.22584.
We investigated whether the injection of 10 mL of normal saline into the subarachnoid space following accidental dural puncture reduced the incidence of postdural puncture headache (PDPH) and the need for epidural blood patch (EBP).
Twenty-eight patients who experienced accidental dural puncture with an epidural needle had 10 mL of normal saline injected into the subarachnoid space. In 22 patients, the injection was performed immediately through the epidural needle. In 6 patients who had intrathecal catheters placed through the epidural needle, the saline was injected through the catheter before removal. All other patients who experienced wet taps during the same period that the study was in progress but did not receive the saline injection served as a control group, 26 in number. Patients with severe or persistent PDPHs were treated with EBP.
Of those patients who received intrathecal normal saline immediately through the epidural needle, 32% developed a headache compared with 62% of controls. Of these, 1 patient who received saline required EBP compared with nine in the control group (P =.004). Of those patients who had intrathecal catheters placed, there were no headaches in the saline group of 6 compared with 3 in the control group of 5, 1 of whom was treated with EBP (P >.05).
The immediate injection of 10 mL intrathecal normal saline after a wet tap significantly reduced the incidence of PDPH and the need for EBP. When an intrathecal catheter had been placed following a wet tap, injection of 10 mL of normal saline before its removal effectively prevented PDPH.
我们研究了在意外硬膜穿破后向蛛网膜下腔注射10毫升生理盐水是否能降低硬膜穿刺后头痛(PDPH)的发生率以及硬膜外血贴(EBP)的需求。
28例使用硬膜外针意外硬膜穿破的患者向蛛网膜下腔注射了10毫升生理盐水。22例患者通过硬膜外针立即进行注射。6例通过硬膜外针置入鞘内导管的患者,在拔除导管前通过导管注射生理盐水。同期进行的所有其他发生硬膜穿破但未接受生理盐水注射的患者作为对照组,共26例。严重或持续性PDPH患者接受EBP治疗。
通过硬膜外针立即接受鞘内生理盐水注射的患者中,32%出现头痛,而对照组为62%。其中,接受生理盐水注射的患者中有1例需要EBP,而对照组有9例(P = 0.004)。在置入鞘内导管的患者中,6例生理盐水组无头痛发生,而5例对照组中有3例头痛,其中1例接受了EBP治疗(P>0.05)。
硬膜穿破后立即鞘内注射10毫升生理盐水可显著降低PDPH的发生率以及EBP的需求。硬膜穿破后置入鞘内导管时,在拔除导管前注射10毫升生理盐水可有效预防PDPH。