Sádecký E, Brezina R, Michalovic M
J Hyg Epidemiol Microbiol Immunol. 1975;19(2):200-6.
Formalin-killed phase I C. burneti organisms containing the protective antigenic component were used for vaccination of heifers against Q fever. None of the vaccinated heifers contracted Q fever, whereas 8 out of 12 (66.6%) control, non-vaccinated heifers became infected when exposed to infection for 3 months in the breed of naturally infected dairy cows. In the vaccinated cattle C. burneti was detected immediately post partum neither in the placenta nor in the colostrum. No shedding of C. burneti in milk has been found so far during 3 years of post-vaccinal observation period. For detecting Q fever antibodies in the blood of vaccinated as well as naturally infected animals MAR was found more sensitive than CFR.
含有保护性抗原成分的福尔马林灭活一期伯纳特柯克斯体用于给小母牛接种预防Q热。接种的小母牛均未感染Q热，而12头未接种的对照小母牛中有8头（66.6%）在与自然感染的奶牛品种一起暴露于感染环境3个月后被感染。在接种的牛中，产后立即在胎盘和初乳中均未检测到伯纳特柯克斯体。在疫苗接种后的3年观察期内，至今未发现牛奶中有伯纳特柯克斯体排出。对于检测接种动物和自然感染动物血液中的Q热抗体，发现微量凝集反应（MAR）比补体结合反应（CFR）更敏感。
