Priestley S J, Taylor J, McAdam C M, Francis P
Department of Emergency Medicine, Sunshine Hospital, Melbourne, Victoria, Australia.
Emerg Med (Fremantle). 2001 Mar;13(1):82-90. doi: 10.1046/j.1442-2026.2001.00184.x.
To introduce a protocol for dissociative sedation using ketamine for children requiring painful procedures within the emergency department.
A medical literature search was performed along with a review of existing ketamine-use protocols in emergency departments from Australia and the United States. Our hospital anaesthetic department and our emergency department nursing staff were closely involved in protocol design. A series of nursing education sessions were held prior to the drug being used within the emergency department. Twenty-eight children aged 1.5-12 years were administered ketamine sedation prior to undergoing a painful procedure. Ketamine was administered either i.m. (dose 3-4 mg/kg) or i.v. (dose 1.00-2.75 mg/kg) depending on physician preference. Midazolam (dose 0.02 mg/kg) and atropine (dose 0.02 mg/kg) were given as adjuncts in the majority of cases.
Onset of sedation was rapid (range 1-7 min) for both routes and provided excellent procedural conditions. Discharge time averaged 103 min (range 67-180 min) from time of drug administration. Side-effects included vomiting, rash, diplopia, salivation and one case of a distressing emergence reaction. On telephone follow up 1-3 days after the sedation, no delayed adverse events were reported.
Ketamine is a safe and effective sedative agent for use in children requiring immobilization to enable performance of a painful procedure. It is important to involve both anaesthetic staff and emergency department nursing staff in sedation protocol development to ensure a smooth introduction. We present a protocol for ketamine use in children undergoing painful procedures within the emergency department.
介绍一种在急诊科对需要进行痛苦操作的儿童使用氯胺酮进行解离性镇静的方案。
进行了医学文献检索,并回顾了澳大利亚和美国急诊科现有的氯胺酮使用方案。我院麻醉科和急诊科护理人员密切参与了方案设计。在急诊科使用该药物之前,举办了一系列护理教育课程。28名年龄在1.5至12岁的儿童在接受痛苦操作前接受了氯胺酮镇静。根据医生的偏好,氯胺酮通过肌肉注射(剂量3 - 4mg/kg)或静脉注射(剂量1.00 - 2.75mg/kg)给药。在大多数情况下,辅助使用咪达唑仑(剂量0.02mg/kg)和阿托品(剂量0.02mg/kg)。
两种给药途径的镇静起效都很快(范围为1 - 7分钟),并提供了良好的操作条件。从给药时间起,平均出院时间为103分钟(范围为67 - 180分钟)。副作用包括呕吐、皮疹、复视、流涎,以及1例令人痛苦的苏醒反应。在镇静后1 - 3天的电话随访中,未报告延迟性不良事件。
氯胺酮是一种安全有效的镇静剂,可用于需要固定以便进行痛苦操作的儿童。麻醉人员和急诊科护理人员都参与镇静方案的制定很重要,以确保顺利引入。我们提出了一种在急诊科对接受痛苦操作的儿童使用氯胺酮的方案。