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一项关于阴道毛滴虫与女性不孕症的研究。

A study on Trichomoniasis vaginalis and female infertility.

作者信息

El-Shazly A M, El-Naggar H M, Soliman M, El-Negeri M, El-Nemr H E, Handousa A E, Morsy T A

机构信息

Department of Parasitology, Faculty Medicine, Mansoura University, Egypt.

出版信息

J Egypt Soc Parasitol. 2001 Aug;31(2):545-53.

Abstract

A total of 280 patients, 240 infertile and 40 pregnant were subjected to thorough history taking, general and local examination for exclusion of organic lesion, laboratory investigations to exclude parasitic, bacterial and fungal infections. Sterile vaginal swab from the posterior fornix was taken, and examined by wet smear preparation, Giemsa staining and cultivation on C.P.L.M. medium for trichomoniasis infection. The mean age of the infertile group was 25.75+/-3.92, and of the control group was 21.6+/-2.38 (in years). The mean duration of infertility was 2.81+/-1.51 (years). Out of 240 infertile women, 18.75% complained of discharge, 17.5% itching, 15.42% dysuria, 14.58% dyspareunia, and 10% had cervical lesion. Of the 40 controls, 5% complained of discharge, 2.5% complained of itching, dysuria, dyspareunia, but none had cervical lesion. Of the total cases (280), 36 (12.9%) had T. vaginalis. The clinical data observed were significantly higher among the infertile group than the control group. Cultures were positive in 14.58% of the infertile group and 2.5% in the control group. The difference between the 2 groups was statistically significant. No doubt, T. vaginalis plays an important role in female infertility.

摘要

共有280例患者,其中240例不孕患者和40例妊娠患者接受了全面的病史采集、全身及局部检查以排除器质性病变,并进行了实验室检查以排除寄生虫、细菌和真菌感染。从后穹窿采集无菌阴道拭子,通过湿涂片制备、吉姆萨染色以及在哥伦比亚多粘菌素B琼脂培养基上培养来检查滴虫感染情况。不孕组的平均年龄为25.75±3.92岁,对照组的平均年龄为21.6±2.38岁(单位:岁)。不孕的平均持续时间为2.81±1.51年(单位:年)。在240例不孕女性中,18.75%有白带异常主诉,17.5%有瘙痒,15.42%有排尿困难,14.58%有性交困难,10%有宫颈病变。在40例对照组中,5%有白带异常主诉,2.5%有瘙痒、排尿困难、性交困难主诉,但均无宫颈病变。在所有病例(280例)中,36例(12.9%)有阴道毛滴虫感染。不孕组观察到的临床数据显著高于对照组。不孕组培养阳性率为14.58%,对照组为2.5%。两组之间的差异具有统计学意义。毫无疑问,阴道毛滴虫在女性不孕中起重要作用。

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