自身免疫性疾病：其发生的原因及部位。
Autoimmune disease: why and where it occurs.
作者信息
Marrack P, Kappler J, Kotzin B L
机构信息
Howard Hughes Medical Institute, University of Colorado Health Sciences Center, Denver, Colorado, USA.
出版信息
Nat Med. 2001 Aug;7(8):899-905. doi: 10.1038/90935.
DOI:10.1038/90935
PMID:11479621
Abstract
Autoimmune disease is controlled by genetic and environmental factors. Both of these affect susceptibility to autoimmunity at three levels: the overall reactivity of the immune system, the specific antigen and its presentation, and the target issue.
摘要
自身免疫性疾病受遗传和环境因素控制。这两种因素在三个层面影响自身免疫易感性：免疫系统的整体反应性、特定抗原及其呈递，以及靶组织。
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