遗传性肌阵挛-肌张力障碍综合征中丘脑腹中间核的神经刺激
Neurostimulation of the ventral intermediate thalamic nucleus in inherited myoclonus-dystonia syndrome.
作者信息
Trottenberg T, Meissner W, Kabus C, Arnold G, Funk T, Einhaupl K M, Kupsch A
机构信息
Department of Neurology, Humboldt-University, Charité-Virchow, Berlin, Germany.
出版信息
Mov Disord. 2001 Jul;16(4):769-71. doi: 10.1002/mds.1119.
We report on the effects of bilateral neurostimulation of the ventral intermediate thalamic nucleus (VIM) in a patient with medically intractable and progressing inherited myoclonus dystonia syndrome (IMDS). Postoperatively, the patient improved by approximately 80% on the modified version of a myoclonus score without any significant change in the dystonic symptoms. This suggests that neurostimulation of the VIM may be an effective treatment for myoclonus in pharmacologically intractable IMDS.
我们报告了对一名患有药物难治性进行性遗传性肌阵挛性肌张力障碍综合征（IMDS）患者进行丘脑腹中间核（VIM）双侧神经刺激的效果。术后，患者在肌阵挛评分的改良版上改善了约80%，而肌张力障碍症状无任何显著变化。这表明，对VIM进行神经刺激可能是药物难治性IMDS中肌阵挛的一种有效治疗方法。
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