Chung K T, Biggers C J
Department of Microbiology and Molecular Cell Sciences, University of Memphis, Memphis, TN 38152, USA.
Perspect Biol Med. 2001 Summer;44(3):379-89. doi: 10.1353/pbm.2001.0044.
Albert Léon Charles Calmette was the first person to develop an anti-venom serum. His work revolutionized the treatment of snakebite in men and domestic animals. He is also well known for his development of the Bacillus Calmette-Guérin (BCG) vaccine for the prevention of tuberculosis. This article reviews the life experiences of this pioneer bioscientist, the current status of BCG in preventing tuberculosis, and the potential of BCG in immunotherapy for cancer.
阿尔贝·莱昂·夏尔·卡尔梅特是第一个研发抗蛇毒血清的人。他的工作彻底改变了人类和家畜蛇咬伤的治疗方法。他还因研发用于预防结核病的卡介苗(BCG)而闻名。本文回顾了这位先驱生物科学家的人生经历、卡介苗在预防结核病方面的现状以及卡介苗在癌症免疫治疗中的潜力。