Penna C, Marino S, Vivot E, Cruañes M C, de D Muñoz J, Cruañes J, Ferraro G, Gutkind G, Martino V
Cátedra de Microbiología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 (1113), Buenos Aires, Argentina.
J Ethnopharmacol. 2001 Sep;77(1):37-40. doi: 10.1016/s0378-8741(01)00266-5.
Different extracts of Sebastiania brasiliensis, Sebastiania klotszchiana, Polygonum punctatum, Lithraea molleoides and Myrcianthes cisplatensis, all plants growing in Entre Ríos Province and traditionally used as antiseptics, were tested against a set of Gram positive and Gram negative bacteria and fungi. All the species, with the exception of M. cisplatensis, presented activity against some of the microorganisms tested. A 50% hydroalcoholic extract of S. brasiliensis was selected for bioguided fractionation. Two antimicrobial compounds identified as methylgallate (MIC 128 microg/ml) and protocatechuic acid (MIC 128 microg/ml) were isolated apart from quercetin, kaempferol, quercitrin and gallic acid.
对塞巴斯蒂亚巴西木、塞巴斯蒂亚克洛茨基木、斑点蓼、软毛石梓和米氏番樱桃的不同提取物进行了测试，这些植物都生长在恩特雷里奥斯省，传统上用作防腐剂，测试对象为一组革兰氏阳性菌、革兰氏阴性菌和真菌。除米氏番樱桃外，所有物种对某些测试微生物均有活性。选择了巴西木的50%水醇提取物进行生物导向分级分离。除了槲皮素、山奈酚、槲皮苷和没食子酸外，还分离出了两种抗菌化合物，分别鉴定为没食子酸甲酯（最低抑菌浓度为128微克/毫升）和原儿茶酸（最低抑菌浓度为128微克/毫升）。
