Chang S T, Chen P F, Chang S C
Department of Forestry, National Taiwan University, No 1 Section 4, Roosevelt, Taipei, Taiwan, ROC.
J Ethnopharmacol. 2001 Sep;77(1):123-7. doi: 10.1016/s0378-8741(01)00273-2.
The antibacterial activities of the essential oils from leaves of two Cinnamomum osmophloeum clones (A and B) and their chemical constituents were investigated in this study. The nine strains of bacteria, including Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis, Staphylococcus aureus, Staphylococcus epidermidis, methicillin-resistant Staphylococcus aureus (MRSA), Klebsiella pneumoniae, Salmonella sp., and Vibrio parahemolyticus, were used in the antibacterial tests. Results from the antibacterial tests demonstrated that the indigenous cinnamon B leaf essential oils had an excellent inhibitory effect. The MICs (minimum inhibitory concentrations) of the B leaf oil were 500 microg/ml against both K. pneumoniae and Salmonella sp. and 250 microg/ml against the other seven strains of bacteria. Cinnamaldehyde possessed the strongest antibacterial activity compared to the other constituents of the essential oils. The MICs of cinnamaldehyde against the E. coli, P. aeruginosa, E. faecalis, S. aureus, S. epidermidis, MRSA, K. pneumoniae, Salmonella sp., and V. parahemolyticus were 500, 1000, 250, 250, 250, 250, 1000, 500, and 250 microg/ml, respectively. These results suggest that C. osmophloeum leaf essential oil and cinnamaldehyde are beneficial to human health, having the potential to be used for medical purposes and to be utilized as anti-bacterial additives in making paper products.
本研究对两个土肉桂无性系（A和B）叶片精油的抗菌活性及其化学成分进行了研究。抗菌试验使用了九种细菌，包括大肠杆菌、铜绿假单胞菌、粪肠球菌、金黄色葡萄球菌、表皮葡萄球菌、耐甲氧西林金黄色葡萄球菌（MRSA）、肺炎克雷伯菌、沙门氏菌和副溶血性弧菌。抗菌试验结果表明，土肉桂B叶精油具有优异的抑制作用。B叶油对肺炎克雷伯菌和沙门氏菌的最低抑菌浓度（MIC）均为500微克/毫升，对其他七种细菌的MIC为250微克/毫升。与精油的其他成分相比，肉桂醛具有最强的抗菌活性。肉桂醛对大肠杆菌、铜绿假单胞菌、粪肠球菌、金黄色葡萄球菌、表皮葡萄球菌、MRSA、肺炎克雷伯菌、沙门氏菌和副溶血性弧菌的MIC分别为500、1000、250、250、250、250、1000、500和250微克/毫升。这些结果表明，土肉桂叶精油和肉桂醛对人体健康有益，具有用于医疗目的以及用作纸品抗菌添加剂的潜力。
