Fathi Mokhtar, Zarrinkavyani Kianoosh, Biranvand Zahra, Mohammad Ali Hashem
Department of Animal Science, Payame Noor University, Tehran, Iran.
Department of Animal Science, Faculty of Agriculture, Ilam University, Ilam, Iran.
Poult Sci. 2025 Jul 28;104(10):105615. doi: 10.1016/j.psj.2025.105615.
A comprehensive experiment was carried out to evaluate the impact of cinnamon nanoparticles (CNPs) on growth performance and hemato-biochemical parameters in broiler chickens. A total of 500 one-day-old Ross 308 chicks were randomly distributed into five dietary treatment groups in a completely randomized design, with each treatment consisting of five replicates containing 20 birds per replicate. The experimental treatments included: A control group receiving a basal diet without supplementation, and four groups supplemented with 150, 300, 450, or 600 mg of CNPs per kg of feed. CNPs were synthesized using an ultrasonic-assisted method. Results demonstrated that dietary inclusion of CNPs at 300-600 mg/kg significantly enhanced average daily weight gain, reduced feed conversion ratio, and decreased mortality (P < 0.05), and with the most pronounced benefits observed at the 450 mg/kg level. Supplementation with CNPs also improved the antioxidant defense system, as indicated by elevated total antioxidant capacity, superoxide dismutase (SOD), and glutathione peroxidase (GPx) activities, along with a marked reduction in serum malondialdehyde (MDA) levels (P < 0.05). These effects were most prominent at 450 mg/kg. Furthermore, supplementation with 450 and 600 mg/kg of cinnamon nanoparticles (CNPs) significantly decreased red blood cell (RBC) count, hemoglobin concentration, hematocrit values, heterophil percentage, and cortisol levels, while significantly increasing lymphocyte percentage (P < 0.05).. Additionally, dietary CNPs led to a reduction in serum concentrations of cholesterol, triglycerides, low-density lipoprotein (LDL), uric acid, creatinine, and aspartate aminotransferase (AST). In conclusion, dietary inclusion of 450 mg/kg CNPs was found to optimally improve growth performance, enhance antioxidant capacity, and positively modulate hematological and biochemical profiles in broiler chickens.
开展了一项综合实验，以评估肉桂纳米颗粒（CNPs）对肉鸡生长性能和血液生化参数的影响。总共500只1日龄的罗斯308雏鸡被完全随机设计分为五个日粮处理组，每个处理有五个重复，每个重复包含20只鸡。实验处理包括：一个接受不添加任何物质的基础日粮的对照组，以及四个分别添加每千克饲料150、300、450或600毫克CNPs的组。CNPs采用超声辅助方法合成。结果表明，日粮中添加300 - 600毫克/千克的CNPs显著提高了平均日增重，降低了饲料转化率，并降低了死亡率（P < 0.05），在450毫克/千克水平观察到最显著的益处。添加CNPs还改善了抗氧化防御系统，表现为总抗氧化能力、超氧化物歧化酶（SOD）和谷胱甘肽过氧化物酶（GPx）活性升高，同时血清丙二醛（MDA）水平显著降低（P < 0.05）。这些影响在450毫克/千克时最为突出。此外，添加450和600毫克/千克的肉桂纳米颗粒（CNPs）显著降低了红细胞（RBC）计数、血红蛋白浓度、血细胞比容值、嗜异性粒细胞百分比和皮质醇水平，同时显著提高了淋巴细胞百分比（P < 0.05）。此外，日粮中的CNPs导致血清胆固醇、甘油三酯、低密度脂蛋白（LDL）、尿酸、肌酐和天冬氨酸转氨酶（AST）浓度降低。总之，发现日粮中添加450毫克/千克的CNPs能最佳地改善肉鸡的生长性能，增强抗氧化能力，并积极调节血液学和生化指标。
