Chipont Benabent E, García-Hermosa P, Alió Y Sanz J L
Instituto Oftalmológico de Alicante, Universidad Miguel Hernández, División de Oftalmología, Alicante.
Arch Soc Esp Oftalmol. 2001 Aug;76(8):505-8.
Our aim is to assess the effectiveness and possible use od a new gel formulation for a LAT solution in minor lacerations repair and to propose its use for daily practice in surgical repair of skin lacerations near ocular structures like eyelids, eyebrows or forhead.
Fifty patients presenting skin lacerations of various origins and locations complying with inclusion criteria were topically anesthesized using LAT gel previous to suturing. Concentrations in final gel solution were as follows: Tetracaine 1.0%. Lidocaine 1.5% and Adrenaline 0.1%. Effectiveness of anaesthesia was assessed by means of various pain evaluation scales filled by patients and physician.
Lidocaine infiltration was performed if any sign of pain was observed. 277 sutures were performed. Lidocaine infiltration was needed in five patients (10%) all of those evidencing lacerations in hands or fingers; no laceration in any facial area nor scalp needed any supplementary lidocaine infiltration. Of the total 254 sutures not needing infiltration, 19 (7.49%) elicited a painful response. 97% of all sutures placed in face and scalp elicited a less painful response and this difference was statistically significant against locations other than head. An average dose of 0.82 ml. of LAT was used in our study (consisting in 12.3 mg of Lidocaine, 8.2 mg of Tetracaine an 0.82 mg of Adrenalin).
LAT gel is an effective alternative for the repair of wounds needing minor surgical procedures, it provides anaesthesia for lacerations in face and scalp of children and adults.
我们的目的是评估一种用于小伤口修复的新型LAT溶液凝胶制剂的有效性及可能的用途，并建议将其用于日常手术修复眼睑、眉毛或额头等眼部结构附近的皮肤裂伤。
50例符合纳入标准、有各种不同来源和部位皮肤裂伤的患者在缝合前使用LAT凝胶进行局部麻醉。最终凝胶溶液中的浓度如下：丁卡因1.0%、利多卡因1.5%和肾上腺素0.1%。通过患者和医生填写的各种疼痛评估量表来评估麻醉效果。
如果观察到任何疼痛迹象，则进行利多卡因浸润。共进行了277针缝合。5例患者（10%）需要进行利多卡因浸润，所有这些患者的手部或手指有裂伤；面部或头皮的任何裂伤均无需补充利多卡因浸润。在总共254针无需浸润的缝合中，有19针（7.49%）引起疼痛反应。面部和头皮上所有缝合中有97%引起的疼痛反应较轻，与头部以外的部位相比，这种差异具有统计学意义。我们的研究中平均使用了0.82毫升LAT（包含12.3毫克利多卡因、8.2毫克丁卡因和0.82毫克肾上腺素）。
LAT凝胶是需要小型外科手术的伤口修复的有效替代方法，它可为儿童和成人面部及头皮的裂伤提供麻醉。
