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丁卡因、肾上腺素(肾上腺素)和可卡因(TAC)与利多卡因、肾上腺素和丁卡因(LET)用于儿童裂伤麻醉的比较。

Tetracaine, epinephrine (adrenalin), and cocaine (TAC) versus lidocaine, epinephrine, and tetracaine (LET) for anesthesia of lacerations in children.

作者信息

Schilling C G, Bank D E, Borchert B A, Klatzko M D, Uden D L

机构信息

Clinical Pharmacy Department, Minneapolis Children's Medical Center, Minnesota.

出版信息

Ann Emerg Med. 1995 Feb;25(2):203-8. doi: 10.1016/s0196-0644(95)70325-x.

Abstract

STUDY OBJECTIVE

To compare the duration of anesthesia experienced with lidocaine, epinephrine, and tetracaine (LET) solution and that with tetracaine, epinephrine (Adrenalin), and cocaine (TAC) solution during suturing of uncomplicated lacerations on the face or scalp.

DESIGN

Double-blind, randomized, controlled trial.

SETTING

The emergency department of a university-affiliated private children's hospital.

PARTICIPANTS

One hundred seventy-one children with lacerations on the face and scalp requiring suturing.

INTERVENTIONS

After standard application of the anesthetic solution, patients were assessed for signs of discomfort before and during laceration repair. Duration of anesthesia during laceration repair was determined on the basis of the length of time after removal of the anesthetic solution to the first sign(s) of discomfort that required additional anesthesia.

RESULTS

There was no statistical difference between TAC and LET in adequacy of anesthesia before suturing or in duration of anesthesia during suturing.

CONCLUSION

LET is an effective alternative to TAC for topical anesthesia during suturing of uncomplicated lacerations on the face and scalp in children.

摘要

研究目的

比较利多卡因、肾上腺素和丁卡因(LET)溶液与丁卡因、肾上腺素(肾上腺素)和可卡因(TAC)溶液在缝合面部或头皮单纯性裂伤时的麻醉持续时间。

设计

双盲、随机、对照试验。

地点

一所大学附属私立儿童医院的急诊科。

参与者

171名面部和头皮有裂伤需要缝合的儿童。

干预措施

在标准应用麻醉溶液后,在裂伤修复前和修复过程中评估患者的不适体征。裂伤修复期间的麻醉持续时间根据去除麻醉溶液后至出现需要额外麻醉的首个不适体征的时间长度来确定。

结果

TAC和LET在缝合前的麻醉充分性或缝合期间的麻醉持续时间方面无统计学差异。

结论

对于儿童面部和头皮单纯性裂伤缝合时的局部麻醉,LET是TAC的有效替代方法。

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