四亚甲基二砜四胺对蟹神经肌肉接头处γ-氨基丁酸引起的膜电导增加的影响。
Effect of tetramethylenedisulphotetramine on the membrane conductance increase produced by gamma-amino-butyric acid at the crab neuromuscular junction.
作者信息
Large W A
出版信息
Br J Pharmacol. 1975 Apr;53(4):598-9. doi: 10.1111/j.1476-5381.1975.tb07401.x.
Abstract
The effect of tetramethylenedisulphotetramine (TETS) on the increase in membrane conductance produced by gamma-aminobutyric acid (GABA) at the hermit crab neuromuscular junction was investigated. TETS produced a dose-dependent antagonism of GABA, which was characterized by a non-parallel shift of the log dose-conductance curve for GABA with a reduced maximal conductance change.
摘要
研究了毒鼠强（TETS）对寄居蟹神经肌肉接头处γ-氨基丁酸（GABA）所引起的膜电导增加的影响。毒鼠强对GABA产生剂量依赖性拮抗作用，其特征为GABA的对数剂量-电导曲线发生非平行位移，最大电导变化减小。
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