Thompson C, Spielman A, Krause P J
Department of Pediatrics, University of Connecticut School of Medicine, Farmington, Connecticut, USA.
Clin Infect Dis. 2001 Sep 1;33(5):676-85. doi: 10.1086/322681. Epub 2001 Aug 6.
The heightened worldwide recognition of the health burden of tickborne infection derives largely from the increasing incidence of Lyme disease, human babesiosis, and human granulocytic ehrlichiosis, both individually and in concert. Because these infections share the same rodent reservoir and tick vector hosts, they can be cotransmitted to human hosts. Indeed, human coinfections involving various combinations of these pathogens are common, and some tend to be particularly severe. Diagnostic procedures and clinical management of the resulting disease syndrome is rendered complex by the diversity of pathogens involved and by the unusual diversity and duration of symptoms.
全球对蜱传感染所致健康负担的关注度日益提高，这在很大程度上源于莱姆病、人巴贝斯虫病和人粒细胞埃立克体病发病率的不断上升，无论是单独还是共同出现。由于这些感染具有相同的啮齿动物宿主和蜱传播媒介，它们可以共同传播给人类宿主。事实上，涉及这些病原体各种组合的人类混合感染很常见，而且有些往往特别严重。由于所涉及病原体的多样性以及症状的异常多样性和持续时间，由此产生的疾病综合征的诊断程序和临床管理变得复杂。
