Pietilä T A, Stendel R, Kombos T, Ramsbacher J, Schulte T, Brock M
Department of Neurosurgery, Benjamin Franklin Medical Center, Free University of Berlin, Berlin, Germany.
Neurol Med Chir (Tokyo). 2001 Jul;41(7):340-4. doi: 10.2176/nmc.41.340.
Retrospective analysis of 165 patients (105 males, 60 females) with a mean age of 21.2 years (range 14 to 25 years) of 6933 surgically treated patients from January 1987 to May 1999 focused on age and sex distribution, body mass, familial predisposition, trauma, histology, and clinical course. The incidence of herniated lumbar discs was 2.3% in patients aged up to 25 years. A valid family history was obtained in 121 patients and a positive history was found in 82 of these patients (67.8%). The patients had a higher body mass index compared to a group of individuals with a similar age structure. Radiography demonstrated bony changes in 124 patients (75.2%), primarily attributable to postural deformities such as scoliosis. The condition of the bony structures seems to be more important than the condition of the disc tissue in the occurrence of this disease in young patients.
对1987年1月至1999年5月间6933例接受手术治疗的患者中的165例(105例男性,60例女性)进行回顾性分析,这些患者的平均年龄为21.2岁(范围14至25岁),分析重点在于年龄和性别分布、体重、家族易感性、创伤、组织学及临床病程。25岁及以下患者中腰椎间盘突出症的发病率为2.3%。在121例患者中获得了有效的家族病史,其中82例患者(67.8%)有阳性家族史。与年龄结构相似的一组个体相比,这些患者的体重指数更高。X线检查显示124例患者(75.2%)有骨质改变,主要归因于姿势性畸形,如脊柱侧弯。在年轻患者中,这种疾病的发生似乎骨质结构状况比椎间盘组织状况更重要。