Flanigan R C, Yonover P M
Department of Urology, Cardinal Bernardin Cancer Center, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, USA.
Curr Oncol Rep. 2001 Sep;3(5):424-32. doi: 10.1007/s11912-001-0029-0.
Metastatic renal cancer is responsive in some cases to immunotherapeutic agents. Indications for nephrectomy in the face of metastatic disease have traditionally included palliation of symptoms caused by the primary tumor, and nephrectomy combined with metastatectomy in patients with resectable metastases. Recent findings from a Southwest Oncology Group trial strongly suggest that cytoreductive nephrectomy, combined with immunotherapy, may also result in improved survival in patients with unresectable metastases.
转移性肾癌在某些情况下对免疫治疗药物有反应。面对转移性疾病时,肾切除术的指征传统上包括缓解原发性肿瘤引起的症状,以及对可切除转移灶患者进行肾切除术联合转移灶切除术。西南肿瘤协作组试验的最新研究结果强烈表明,减瘤性肾切除术联合免疫治疗,也可能提高不可切除转移灶患者的生存率。